Compile Data Set for Download or QSAR
Found 32 with Last Name = 'wilkins' and Initial = 'lh'
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119791(1-Decyl-3-((S)-1-methyl-pyrrolidin-2-yl)-pyridiniu...)copy SMILEScopy InChI
Affinity DataKi:  90nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143302((S)-1-dodecyl-3-(1-methylpyrrolidin-2-yl)pyridiniu...)copy SMILEScopy InChI
Affinity DataKi:  140nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143304(3-(1-methylpyrrolidin-2-yl)-1-[6-(3-(1-methylpyrro...)copy SMILEScopy InChI
Affinity DataKi:  1.95E+3nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143293(1-[6-(pyridinium-1-yl)tetradecyl]pyridinium; Dibro...)copy SMILEScopy InChI
Affinity DataKi:  9.15E+3nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143301((2-Hydroxy-ethyl)-dimethyl-octyl-ammonium | CHEMBL...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143312(CHEMBL53882 | Hexyl-(2-hydroxy-ethyl)-dimethyl-amm...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119801((S)-3-(1-methylpyrrolidin-2-yl)-1-octylpyridinium ...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of [3H]-MLA binding to Nicotinic acetylcholine receptor alpha7 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143309(1-Decyl-pyridinium; iodide | CHEMBL55297)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119801((S)-3-(1-methylpyrrolidin-2-yl)-1-octylpyridinium ...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119791(1-Decyl-3-((S)-1-methyl-pyrrolidin-2-yl)-pyridiniu...)copy SMILEScopy InChI
Affinity DataKi:  2.70E+4nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143293(1-[6-(pyridinium-1-yl)tetradecyl]pyridinium; Dibro...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of [3H]-MLA binding to Nicotinic acetylcholine receptor alpha7 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143307(1-Pentadecyl-pyridinium; bromide | CHEMBL55479)copy SMILEScopy InChI
Affinity DataKi:  3.80E+4nMAssay Description:Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119801((S)-3-(1-methylpyrrolidin-2-yl)-1-octylpyridinium ...)copy SMILEScopy InChI
Affinity DataKi:  4.90E+4nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143296(1-Butyl-pyridinium | CHEMBL443525)copy SMILEScopy InChI
Affinity DataKi:  2.50E+5nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetSodium- and chloride-dependent creatine transporter 1(Rattus norvegicus)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143295(1-Octyl-pyridinium; iodide | 1-octylpyridinium iod...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+5nMAssay Description:Binding affinity towards blood brain barrier choline transporter at 10 microM using rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143302((S)-1-dodecyl-3-(1-methylpyrrolidin-2-yl)pyridiniu...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143305((3aR,9bS)-6-Decyl-1-methyl-2,3,3a,4,5,9b-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143303((3aS,9bR)-1-Methyl-8-undecyl-2,3,3a,4,5,9b-hexahyd...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143306((3aR,9bS)-1-Methyl-6-octyl-2,3,3a,4,5,9b-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143300((3aR,9bS)-1-Methyl-6-undecyl-2,3,3a,4,5,9b-hexahyd...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143298((3aS,9bR)-1-Methyl-8-octyl-2,3,3a,4,5,9b-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143294(1-Icosyl-pyridinium; bromide | 1-icosylpyridinium ...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143309(1-Decyl-pyridinium; iodide | CHEMBL55297)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143304(3-(1-methylpyrrolidin-2-yl)-1-[6-(3-(1-methylpyrro...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143297((3aS,9bR)-8-Dodecyl-1-methyl-2,3,3a,4,5,9b-hexahyd...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143308(1-Dodecyl-pyridinium; iodide | CHEMBL540201)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143311((3aR,9bS)-1-Methyl-6-nonyl-2,3,3a,4,5,9b-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143307(1-Pentadecyl-pyridinium; bromide | CHEMBL55479)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143299((3aS,9bR)-8-Decyl-1-methyl-2,3,3a,4,5,9b-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50119801((S)-3-(1-methylpyrrolidin-2-yl)-1-octylpyridinium ...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143310((3aS,9bR)-1-Methyl-8-nonyl-2,3,3a,4,5,9b-hexahydro...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibitory activity of the compound against nAChR mediated nicotine-evoked [3H]-DA overflow using rat striatal slicesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rattus norvegicus (Rat))
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50143293(1-[6-(pyridinium-1-yl)tetradecyl]pyridinium; Dibro...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of [3H]-nicotine binding to Nicotinic acetylcholine receptor alpha4-beta2 in rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N80JPPubMed