Compile Data Set for Download or QSAR
Found 61 with Last Name = 'stewart' and Initial = 'lj'
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303652(1-(4-Phenoxyphenyl)piperazine | CHEMBL576512)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303656((R)-2-[4-(4-Thiophen-3-yl-benzyl)phenoxymethyl]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303657(3-{(R)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303650((R)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294161((R)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303649(4-{(S)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMedMMDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303649(4-{(S)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrroli...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMedMMDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294161((R)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294161((R)-4-(2-((4-(4-chlorophenoxy)phenoxy)methyl)pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294162((R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen...)copy SMILEScopy InChI
Affinity DataIC50: 81nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303648((2R)-2-[(4-benzylphenoxy)methyl]pyrrolidine | (R)-...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294163((R)-N-benzyl-4-(pyrrolidin-2-ylmethoxy)aniline | C...)copy SMILEScopy InChI
Affinity DataIC50: 157nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294162((R)-(4-(pyrrolidin-2-ylmethoxy)phenyl)(4-(thiophen...)copy SMILEScopy InChI
Affinity DataIC50: 189nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294163((R)-N-benzyl-4-(pyrrolidin-2-ylmethoxy)aniline | C...)copy SMILEScopy InChI
Affinity DataIC50: 207nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303658((2S)-2-[(4-Benzylphenoxy)methyl]pyrrolidine | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 244nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303651(1-[4-(4-Iodophenoxy)phenyl]piperazine | CHEMBL5672...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303648((2R)-2-[(4-benzylphenoxy)methyl]pyrrolidine | (R)-...)copy SMILEScopy InChI
Affinity DataIC50: 449nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303650((R)-2-[4-(4-Chlorophenoxy)phenoxymethyl]pyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 533nMAssay Description:Inhibition of human LTA4H hydrolysis assessed as inhibition of Ca2+ ionophore-stimulated LTB4 formation in human whole blood by ELISAChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303653(4-[2-(4-Benzylphenoxy)ethyl]pyridine | CHEMBL57813...)copy SMILEScopy InChI
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7NJDPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294164(1-(2,2'-bithiophen-5-yl)methanamine | 2,2'-bithiop...)copy SMILEScopy InChI
Affinity DataIC50: 3.89E+4nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294164(1-(2,2'-bithiophen-5-yl)methanamine | 2,2'-bithiop...)copy SMILEScopy InChI
Affinity DataIC50: 7.52E+4nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294165((4-(thiophen-2-yl)phenyl)methanamine | 1-(4-thioph...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+4nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294165((4-(thiophen-2-yl)phenyl)methanamine | 1-(4-thioph...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294165((4-(thiophen-2-yl)phenyl)methanamine | 1-(4-thioph...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50085531(3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294166(CHEMBL558285 | pyridin-4-yl(4-(2-(pyrrolidin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303654(CHEMBL565599 | pyridin-4-yl(4-(2-(pyrrolidin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.99E+5nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294166(CHEMBL558285 | pyridin-4-yl(4-(2-(pyrrolidin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.02E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataIC50: 2.12E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294167(5-(2-(pyrrolidin-1-yl)ethoxy)-1H-indole | CHEMBL56...)copy SMILEScopy InChI
Affinity DataIC50: 2.34E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50085531(3,4',5-trihydroxybibenzyl | 5-(4-hydroxyphenethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.47E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM13337(3-(benzyloxy)pyridin-2-amine | EN300-247019 | Pyri...)copy SMILEScopy InChI
Affinity DataIC50: 3.08E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294167(5-(2-(pyrrolidin-1-yl)ethoxy)-1H-indole | CHEMBL56...)copy SMILEScopy InChI
Affinity DataIC50: 3.21E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataIC50: 3.66E+5nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM13337(3-(benzyloxy)pyridin-2-amine | EN300-247019 | Pyri...)copy SMILEScopy InChI
Affinity DataIC50: 6.19E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294168(1-(2-(1H-indol-5-yloxy)ethyl)piperidine-4-carboxyl...)copy SMILEScopy InChI
Affinity DataIC50: 9.66E+5nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMedMMDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMedMMDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294169(5-chloro-1H-indole | CHEMBL555013)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294170(5-fluoro-1H-indole | CHEMBL555457)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMedMMDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294171(CHEMBL549343 | N-methyl-1-(2-(thiophen-2-yl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294172(CHEMBL264669 | N-(pyridin-3-ylmethyl)aniline | N-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50293592(4-(2-Aminothiazol-4-yl)phenol | 4-(2-amino-1,3-thi...)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMedMMDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294168(1-(2-(1H-indol-5-yloxy)ethyl)piperidine-4-carboxyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+6nMAssay Description:Inhibition of peptidase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRAREMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294169(5-chloro-1H-indole | CHEMBL555013)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294172(CHEMBL264669 | N-(pyridin-3-ylmethyl)aniline | N-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50303655(2-(pyridin-3-ylmethoxy)aniline | CHEMBL566838)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of human recombinant LTA4H hydrolysis assessed as inhibition of LTB4 formation by LC-MS/MSChecked by AuthorMore data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM32212(1H-indol-5-ol | cid_16054)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMedMMDB
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294171(CHEMBL549343 | N-methyl-1-(2-(thiophen-2-yl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
deCODE Chemistry, Inc.

Curated by ChEMBL
LigandPNGBDBM50294170(5-fluoro-1H-indole | CHEMBL555457)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMAssay Description:Inhibition of hydrolase activity of human recombinant LTA4H expressed in Escherichia coli BL21-AI/pRARE assessed as LTB4 formation by tandem quadrupo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47P6NPubMedMMDB
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