Compile Data Set for Download or QSAR
Found 23 with Last Name = 'xue' and Initial = 'lj'
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552232(CHEMBL4776624)copy SMILES
Affinity DataKi:  68nMAssay Description:Mixed inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human CES2A using 4-methylumbelliferone as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552232(CHEMBL4776624)copy SMILES
Affinity DataIC50: 52nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552233(CHEMBL4748399)copy SMILES
Affinity DataIC50: 380nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552231(CHEMBL4740149)copy SMILES
Affinity DataIC50: 610nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556551(CHEMBL4780848)copy SMILES
Affinity DataIC50: 630nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556550(CHEMBL4748929)copy SMILES
Affinity DataIC50: 810nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552214(CHEMBL4747287)copy SMILES
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552212(CHEMBL4761197)copy SMILES
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552215(CHEMBL4751728)copy SMILES
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552229(CHEMBL4752404)copy SMILES
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556549(CHEMBL4764489)copy SMILES
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552230(CHEMBL4745825)copy SMILES
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552228(CHEMBL4756815)copy SMILES
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552232(CHEMBL4776624)copy SMILES
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibition of hCES2A in human HepG2 cells assessed as reduction in fluorogenic substrate NCEN hydrolysis preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556547(CHEMBL4759252)copy SMILES
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552219(CHEMBL4170979)copy SMILES
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556546(CHEMBL4748860)copy SMILES
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556548(CHEMBL4786407)copy SMILES
Affinity DataIC50: 1.82E+4nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))TBA
LigandPNGBDBM50556545(CHEMBL4748905)copy SMILES
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50552232(CHEMBL4776624)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of hCES1A in human liver microsome assessed as reduction in D-Iuciferin methyl ester hydrolysis preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50552232(CHEMBL4776624)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BChE in human plasma assessed as reduction in butyrylthiocholineiodide hydrolysis preincubated for 3 mins followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed