Compile Data Set for Download or QSAR
Found 1303 with Last Name = 'bush' and Initial = 'lr'
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337844(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)-4-met...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433654(US10562878, Compound 115)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337831(CHEMBL1683899 | N,N-dimethyl-1-(1-(naphthalen-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433734(US10562878, Compound 206 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337831(CHEMBL1683899 | N,N-dimethyl-1-(1-(naphthalen-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337915((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-3-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50334781(CHEMBL1642912 | Cis-2-((2S,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337818(CHEMBL1683876 | N-((1-(3,4-dichlorophenyl)cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50334773(CHEMBL1642904 | trans-((2R,4S)-4-(3,4-dichlorophen...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433711(US10562878, Compound 268 | US10562878, Compound 26...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337829(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337830(CHEMBL1683875 | N-((1-(3,4-dichlorophenyl)cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337913((+/-)-N,N-dimethyl-1-(1-(naphthalen-2-yl)cyclohexy...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433905(US10562878, Compound 161 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433675(US10562878, Compound 72)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337823(1-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)pyrrol...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337832(CHEMBL1683873 | N-((1-(3,4-dichlorophenyl)cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50334787(CHEMBL1642902 | cis-((2S,4S)-4-(3,4-dichlorophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433842(US10562878, Compound 63 E1 | US10562878, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337822(4-((1-(3,4-dichlorophenyl)cyclohexyl)methyl)morpho...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433736(US10562878, Compound 147 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337910((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433673(US10562878, Compound 254 | US10562878, Compound 26...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433764(US10562878, Compound 273 | US10562878, Compound 27...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337831(CHEMBL1683899 | N,N-dimethyl-1-(1-(naphthalen-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Quantification of 5-HT uptake was performed using synaptosomes isolated in a 0.32M sucrose buffer from a male Wistar rat cortex. The uptake of radiol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337833(CHEMBL1683902 | N,N-dimethyl-1-(1-(naphthalen-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human serotonin reuptake transporter was assayed using the recombinant human serotonin transporter expressed in HEK-293 cells. HEK-293 ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337833(CHEMBL1683902 | N,N-dimethyl-1-(1-(naphthalen-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433652(US10562878, Compound 116)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433835(US10562878, Compound 233 | US10562878, Compound 23...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50334770(CHEMBL1642900 | cis-(2S,4S)-4-(3,4-dichlorophenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50028094((1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50149940(CHEMBL3770651 | US10562878, Compound 203)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337912(CHEMBL1684056 | N-methyl-1-(1-(naphthalen-2-yl)cyc...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433833(US10562878, Compound 293)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433836(US10562878, Compound 62 E1 | US10562878, Compound ...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337829(1-(1-(3,4-dichlorophenyl)cyclohexyl)-N,N-dimethylm...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337834(CHEMBL1683872 | N-((1-(3,4-dichlorophenyl)cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433566(US10562878, Compound 172 E1 | US10562878, Compound...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433911(US10562878, Compound 252)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337914((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)propan-1...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetNeuroepithelial cell-transforming 1(Rat)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337910((+/-)-1-(1-(3,4-dichlorophenyl)cyclohexyl)-N-methy...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Quantification of norepinephrine uptake was performed using synaptosomes isolated in a 0.32 M sucrose buffer from a male Wistar rat hypothalamus. The...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM30130(CHEMBL1201082 | CHEMBL41 | Fluoxetin | Fluoxetine ...)copy SMILEScopy InChI
Affinity DataIC50: 5.20nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639Q0MPubMedDrugBank
TargetNeuroepithelial cell-transforming gene 1 protein(Homo sapiens)
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM50337818(CHEMBL1683876 | N-((1-(3,4-dichlorophenyl)cyclohex...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human norepinephrine reuptake transporter was assayed using the recombinant human norepinephrine transporter expressed in either HEK293...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
SUNOVION PHARAMCEUTICALS INC.

US Patent
LigandPNGBDBM433911(US10562878, Compound 252)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human dopamine reuptake transporter was assayed using the recombinant human dopamine transporter expressed in either CHO-K1 or HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2XP77BXUS Patent
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