Found 140 with Last Name = 'botros' and Initial = 'ls' 
Affinity DataKi: 5nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 81nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...More data for this Ligand-Target Pair
Affinity DataKi: 204nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...More data for this Ligand-Target Pair
Affinity DataKi: 436nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...More data for this Ligand-Target Pair
Affinity DataKi: 977nMAssay Description:Displacement of [3H]strychnine from human glycine receptor subunit alpha-1 expressed in HEK293 cell membranes preincubated for 30 mins followed by [3...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the later state of compou...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 55nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the later state of compou...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in HEK293 cells assessed as reduction in glycine-induced currents by whol...More data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the later state of compou...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 134nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the onset of compound app...More data for this Ligand-Target Pair
Affinity DataIC50: 137nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the later state of compou...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 158nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the later state of compou...More data for this Ligand-Target Pair
Affinity DataIC50: 170nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 204nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 427nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 513nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 513nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 676nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 720nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 741nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 776nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in HEK293 cells assessed as reduction in glycine-induced currents by whol...More data for this Ligand-Target Pair
Affinity DataIC50: 852nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the onset of compound app...More data for this Ligand-Target Pair
Affinity DataIC50: 871nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.23E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in HEK293 cells assessed as reduction in glycine-induced currents by whol...More data for this Ligand-Target Pair
Affinity DataIC50: 1.34E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 assessed as inhibition of glycine-induced current measured at the onset of compound app...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in HEK293 cells assessed as reduction in glycine-induced currents by whole-ce...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1 expressed in human tsA201 cells assessed as reduction in glycine-induced response incub...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+3nMAssay Description:Antagonist activity at human glycine receptor subunit alpha-1beta expressed in human tsA201 cells assessed as reduction in glycine-induced response i...More data for this Ligand-Target Pair
