Compile Data Set for Download or QSAR
Found 88 with Last Name = 'zou' and Initial = 'lw'
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154561(CHEMBL3774603)copy SMILEScopy InChI
Affinity DataKi:  42nMAssay Description:Competitive inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)copy SMILES
Affinity DataKi:  68nMAssay Description:Mixed inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571105(CHEMBL4851375)copy SMILES
Affinity DataKi:  90nMAssay Description:Non-competitive inhibition of CES2 in human liver microsomes using fluorescein diacetate as substrate by Lineweaver-Burk plot based Michelis-Menten e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of human CES2A using 4-methylumbelliferone as a substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154561(CHEMBL3774603)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)copy SMILES
Affinity DataIC50: 52nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571105(CHEMBL4851375)copy SMILES
Affinity DataIC50: 130nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552233(CHEMBL4748399)copy SMILES
Affinity DataIC50: 380nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552231(CHEMBL4740149)copy SMILES
Affinity DataIC50: 610nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556551(CHEMBL4780848)copy SMILES
Affinity DataIC50: 630nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154559(CHEMBL2151605)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556550(CHEMBL4748929)copy SMILES
Affinity DataIC50: 810nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552214(CHEMBL4747287)copy SMILES
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552212(CHEMBL4761197)copy SMILES
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552215(CHEMBL4751728)copy SMILES
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50233165(CHEMBL1222042)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552229(CHEMBL4752404)copy SMILES
Affinity DataIC50: 1.62E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556549(CHEMBL4764489)copy SMILES
Affinity DataIC50: 2.81E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552230(CHEMBL4745825)copy SMILES
Affinity DataIC50: 2.86E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552228(CHEMBL4756815)copy SMILES
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154558(CHEMBL3775320)copy SMILEScopy InChI
Affinity DataIC50: 3.42E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50084040(Bavachinin A)copy SMILEScopy InChI
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571096(CHEMBL4871900)copy SMILES
Affinity DataIC50: 3.82E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154554(CHEMBL3775391)copy SMILEScopy InChI
Affinity DataIC50: 3.95E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154560(CHEMBL3775118)copy SMILEScopy InChI
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50084040(Bavachinin A)copy SMILEScopy InChI
Affinity DataIC50: 4.31E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552232(CHEMBL4776624)copy SMILES
Affinity DataIC50: 4.45E+3nMAssay Description:Inhibition of hCES2A in human HepG2 cells assessed as reduction in fluorogenic substrate NCEN hydrolysis preincubated for 1 hr followed by substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571080(CHEMBL4875001)copy SMILES
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556547(CHEMBL4759252)copy SMILES
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50058817(CHEMBL1271483)copy SMILEScopy InChI
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154562(CHEMBL1271536)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50552219(CHEMBL4170979)copy SMILES
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)copy SMILEScopy InChI
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571094(CHEMBL4864916)copy SMILES
Affinity DataIC50: 6.19E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50130915(CHEBI:3122 | CHEMBL1231178)copy SMILEScopy InChI
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571083(CHEMBL4848122)copy SMILES
Affinity DataIC50: 6.68E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50017698(4-(4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl)-N,N...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50346605(CHEMBL487933)copy SMILEScopy InChI
Affinity DataIC50: 6.95E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154555(CHEMBL3775916)copy SMILEScopy InChI
Affinity DataIC50: 6.99E+3nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571081(CHEMBL4871946)copy SMILES
Affinity DataIC50: 7.11E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154556(CHEMBL1271200)copy SMILEScopy InChI
Affinity DataIC50: 7.36E+3nMAssay Description:Inhibition of CE2 in human liver microsomes using fluorescein diacetate as substrate preincubated for 10 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571092(CHEMBL4870040)copy SMILES
Affinity DataIC50: 7.76E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571085(CHEMBL4853642)copy SMILES
Affinity DataIC50: 8.24E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571091(CHEMBL4870605)copy SMILES
Affinity DataIC50: 9.04E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571104(CHEMBL4850016)copy SMILES
Affinity DataIC50: 9.12E+3nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50154554(CHEMBL3775391)copy SMILEScopy InChI
Affinity DataIC50: 9.13E+3nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetLiver carboxylesterase 1(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50346605(CHEMBL487933)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of CE1 in human liver microsomes using 2-(2-Benzoyl-3-methoxyphenyl) benzothiazole as substrate preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ63D6PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50556546(CHEMBL4748860)copy SMILES
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ8CB7PubMed
TargetCocaine esterase(Homo sapiens (Human))
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50571089(CHEMBL4866857)copy SMILES
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of CES2 in human liver microsomes assessed as reduction in substrate hydrolysis using fluorescein diacetate as substrate preincubated for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0DQPPubMed
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