Compile Data Set for Download or QSAR
Found 115 with Last Name = 'bosserman' and Initial = 'm'
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144342(3-((1R,3S)-3-Amino-cyclopentyl)-2-[1-(3,3-dimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144333(3-(6-Amino-5-methyl-pyridin-3-yl)-2-[1-(4-methyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144336(3-(6-Amino-5-methyl-pyridin-3-yl)-2-[1-(3-methyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144342(3-((1R,3S)-3-Amino-cyclopentyl)-2-[1-(3,3-dimethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144337(3-(6-Amino-pyridin-3-yl)-2-[1-(4-methyl-pentyl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144337(3-(6-Amino-pyridin-3-yl)-2-[1-(4-methyl-pentyl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135936(3-(6-Amino-pyridin-3-yl)-2-(1-butyl-1H-imidazol-4-...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135939(3-(4,4-Diamino-but-3-enylsulfanyl)-2-mercaptomethy...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144333(3-(6-Amino-5-methyl-pyridin-3-yl)-2-[1-(4-methyl-p...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase M(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135939(3-(4,4-Diamino-but-3-enylsulfanyl)-2-mercaptomethy...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:In vitro inhibition of purified Carboxypeptidase M (CPM) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144316(3-(6-Amino-5-methyl-pyridin-3-yl)-2-(1H-imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135935(3-(6-Amino-pyridin-3-yl)-2-(1-benzyl-1H-imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144336(3-(6-Amino-5-methyl-pyridin-3-yl)-2-[1-(3-methyl-b...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144317(6-Amino-2-[1-(3-methyl-butyl)-1H-imidazol-4-yl]-he...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135940(3-(6-Amino-pyridin-3-yl)-2-(1-ethyl-1H-imidazol-4-...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135937(3-(6-Amino-pyridin-3-yl)-2-(1-methyl-1H-imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135938(3-(6-Amino-pyridin-3-yl)-2-(1-isopropyl-1H-imidazo...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135933(3-(6-Amino-pyridin-3-yl)-2-(1H-imidazol-4-yl)-prop...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135933(3-(6-Amino-pyridin-3-yl)-2-(1H-imidazol-4-yl)-prop...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144316(3-(6-Amino-5-methyl-pyridin-3-yl)-2-(1H-imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144325(3-((1R,3S)-3-Amino-cyclopentyl)-2-(1-ethyl-1H-imid...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144942(2'-C-Me-guanosine | 2'-C-methyl-guanosine | 2'-C-m...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2BQ3PubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144325(3-((1R,3S)-3-Amino-cyclopentyl)-2-(1-ethyl-1H-imid...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144317(6-Amino-2-[1-(3-methyl-butyl)-1H-imidazol-4-yl]-he...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144322(6-Amino-2-(1H-imidazol-4-yl)-5-methyl-hexanoic aci...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144320(6-Amino-2-(1H-imidazol-4-yl)-5,5-dimethyl-hexanoic...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase A1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50121929((phenylmethyl)butanedioic acid | 2-benzylbutanedio...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144334(6-Amino-2-(1H-imidazol-4-yl)-hexanoic acid | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144320(6-Amino-2-(1H-imidazol-4-yl)-5,5-dimethyl-hexanoic...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144937(2-Amino-9-((2R,3R,5S)-3-hydroxy-5-hydroxymethyl-te...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2BQ3PubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135933(3-(6-Amino-pyridin-3-yl)-2-(1H-imidazol-4-yl)-prop...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase A1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase A1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135934(3-(6-Amino-pyridin-3-yl)-2-[1-(3-methyl-butyl)-1H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144323(3-(6-Amino-4-methyl-pyridin-3-yl)-2-(1H-imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144322(6-Amino-2-(1H-imidazol-4-yl)-5-methyl-hexanoic aci...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50121929((phenylmethyl)butanedioic acid | 2-benzylbutanedio...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:In vitro inhibition of purified Carboxypeptidase B (CPB) by clot lysis assay in human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144947(2-Amino-9-((2R,3R,4R,5R)-4-hydroxy-5-hydroxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2BQ3PubMed
TargetCarboxypeptidase A1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50100009(2-(1H-Imidazol-4-yl)-3-phenyl-propionic acid | 2-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:In vitro inhibition of Carboxypeptidase A (CPA) was determined by clot lysis assay using human plasmaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1J0ZPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144938(2-Amino-9-((2R,3S,4S,5R)-4-fluoro-3-hydroxy-5-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2BQ3PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144948((2R,3R,4R,5R)-2-(6-amino-9H-purin-9-yl)-5-(hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2BQ3PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144949((2R,3R,4R,5R)-2-(2,6-diamino-9H-purin-9-yl)-5-(hyd...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2BQ3PubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144329(3-Imidazo[1,2-a]pyridin-6-yl-2-(1H-imidazol-4-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144334(6-Amino-2-(1H-imidazol-4-yl)-hexanoic acid | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human carboxypeptidase B (CPB)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus)
Isis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50144934((2R,3R,4R,5R)-2-(6-hydroxy-9H-purin-9-yl)-5-(hydro...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition HCV NS5B-mediated RNA synthesisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2BQ3PubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144324(7-Amino-2-(1H-imidazol-4-yl)-heptanoic acid | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144332(3-(6-Amino-5-chloro-pyridin-3-yl)-2-(1H-imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
TargetCarboxypeptidase B2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50144339(3-(6-Amino-2-methyl-pyridin-3-yl)-2-(1H-imidazol-4...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibitory potency against human TAFIa (thrombin-activatable fibrinolysis inhibitor)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N8797SPubMed
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