Compile Data Set for Download or QSAR
Found 352 with Last Name = 'burnet' and Initial = 'm'
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583707(CHEMBL5074371)copy SMILES
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583677(CHEMBL5074857)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50425382(CHEMBL2316197)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583681(CHEMBL5085015)copy SMILES
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L858R](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583674(CHEMBL5094430)copy SMILES
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583696(CHEMBL5086455)copy SMILES
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583688(CHEMBL5082978)copy SMILES
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetEpidermal growth factor receptor [1-751,75360-1210](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-746,753-1210,P753S](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [L861Q](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583690(CHEMBL5093265)copy SMILES
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583669(CHEMBL5093965)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583667(CHEMBL5094431)copy SMILES
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583660(CHEMBL5080423)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583662(CHEMBL5080798)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583676(CHEMBL5084842)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583671(CHEMBL5078955)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetEpidermal growth factor receptor [1-746,750-1210,A750P](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583678(CHEMBL5081438)copy SMILES
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583664(CHEMBL5080807)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583691(CHEMBL5076216)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123PPUS Patent
TargetEpidermal growth factor receptor [G719C](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50392175(CHEMBL2152944)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human p38 MAPK alphaMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583672(CHEMBL5085427)copy SMILES
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583670(CHEMBL5084172)copy SMILES
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583701(CHEMBL5083671)copy SMILES
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583689(CHEMBL5072899)copy SMILES
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583683(CHEMBL5074845)copy SMILES
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583655(CHEMBL5083321)copy SMILES
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583710(CHEMBL5087840)copy SMILES
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583659(CHEMBL5077679)copy SMILES
Affinity DataIC50: 5.90nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583700(CHEMBL5083496)copy SMILES
Affinity DataIC50: 6.10nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583663(CHEMBL5078332)copy SMILES
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583656(CHEMBL5086200)copy SMILES
Affinity DataIC50: 6.40nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetEpidermal growth factor receptor [G719S](Homo sapiens (Human))
Synovo GmbH

US Patent
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMpH: 7.5 T: 2°CAssay Description:FlashPlates from Perkin Elmer (Boston, Mass., USA) with a 50 μl reaction volume are used. The reaction cocktail was pipetted in 4 steps in the fol...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583680(CHEMBL5089367)copy SMILES
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583654(CHEMBL5077220)copy SMILES
Affinity DataIC50: 7.80nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583686(CHEMBL5092751)copy SMILES
Affinity DataIC50: 8nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583692(CHEMBL5087468)copy SMILES
Affinity DataIC50: 8.40nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583682(CHEMBL5086246)copy SMILES
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM15244(5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfa...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Antagonist activity at p38 MAPK alpha (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583673(CHEMBL5090615)copy SMILES
Affinity DataIC50: 10nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583687(CHEMBL5091208)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583708(CHEMBL5077769)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583675(CHEMBL5087601)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))TBA
LigandPNGBDBM50583684(CHEMBL5079750)copy SMILES
Affinity DataIC50: 12nMAssay Description:Inhibition of human p38 MAPK alpha incubated for 1 hr by photometric methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B355RPubMed
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