Compile Data Set for Download or QSAR
Found 207 with Last Name = 'cockerill' and Initial = 'm'
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081185(CHEMBL3421963)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081186(CHEMBL3421962)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081174(CHEMBL3421968)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081188(CHEMBL3421981)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081181(CHEMBL3421967)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081180(CHEMBL3421969)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081179(CHEMBL3421970)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081191(CHEMBL3421978)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081189(CHEMBL3421980)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081178(CHEMBL3421971)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081182(CHEMBL3421966)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081193(CHEMBL3421976)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081192(CHEMBL3421977)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081184(CHEMBL3421964)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081190(CHEMBL3421979)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081177(CHEMBL3421973)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant full length C-terminal His6-tagged CDK2 expressed in baculovirus infected Sf21 insect cells using fluorescence substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081173(CHEMBL3421972)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of human wild-type TTK (514 to 795) expressed in insect sf9 cellsMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081175(CHEMBL3421975)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081177(CHEMBL3421973)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081177(CHEMBL3421973)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged IGF-1R using fluorescence substrate after 80 mins by caliper off-chip incubation mobility shif...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of GST-tagged Dyrk1A (unknown origin) expressed in Escherichia coli using [33P]ATP[gammaP]/DYRKtide as substrate after 5 mins by liquid sc...More data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081183(CHEMBL3421965)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081174(CHEMBL3421968)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM30202(Pyrrolopyridine, 33)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081179(CHEMBL3421970)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged IGF-1R using fluorescence substrate after 80 mins by caliper off-chip incubation mobility shif...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081180(CHEMBL3421969)copy SMILEScopy InChI
Affinity DataIC50: 72nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged IGF-1R using fluorescence substrate after 80 mins by caliper off-chip incubation mobility shif...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081179(CHEMBL3421970)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081187(CHEMBL3421636)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081181(CHEMBL3421967)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50550438(CHEMBL4798388)copy SMILES
Affinity DataIC50: 90nMAssay Description:Inhibition of active recombinant human N-terminal His-tagged 11-betaHSD1 expressed in Escherichia coli using cortisone, NADPH and glucose-6-phosphate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081176(CHEMBL3421974)copy SMILEScopy InChI
Affinity DataIC50: 98nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081173(CHEMBL3421972)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of recombinant Dyrk1B (unknown origin) using FITC-Asp-His-Thr-Gly-Phe-Leu-Thr-Glu-Tyr-Val-Ala-Thr-Arg-NH2 as substrate after 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 166nMAssay Description:Inhibition of GST-tagged Dyrk1B (unknown origin) expressed in Escherichia coli using [33P]ATP[gammaP]/DYRKtide as substrate after 5 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081178(CHEMBL3421971)copy SMILEScopy InChI
Affinity DataIC50: 168nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081191(CHEMBL3421978)copy SMILEScopy InChI
Affinity DataIC50: 192nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081189(CHEMBL3421980)copy SMILEScopy InChI
Affinity DataIC50: 194nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550442(CHEMBL4747862)copy SMILES
Affinity DataIC50: 230nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550438(CHEMBL4798388)copy SMILES
Affinity DataIC50: 270nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550441(CHEMBL4790846)copy SMILES
Affinity DataIC50: 270nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081185(CHEMBL3421963)copy SMILEScopy InChI
Affinity DataIC50: 282nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081188(CHEMBL3421981)copy SMILEScopy InChI
Affinity DataIC50: 314nMAssay Description:Inhibition of human recombinant full length C-terminal His6-tagged CDK2 expressed in baculovirus infected Sf21 insect cells using fluorescence substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081188(CHEMBL3421981)copy SMILEScopy InChI
Affinity DataIC50: 378nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081186(CHEMBL3421962)copy SMILEScopy InChI
Affinity DataIC50: 453nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550438(CHEMBL4798388)copy SMILES
Affinity DataIC50: 470nMAssay Description:Inhibition of IDH1 R132C mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081186(CHEMBL3421962)copy SMILEScopy InChI
Affinity DataIC50: 577nMAssay Description:Inhibition of human recombinant full length C-terminal His6-tagged CDK2 expressed in baculovirus infected Sf21 insect cells using fluorescence substr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550483(CHEMBL4751940)copy SMILES
Affinity DataIC50: 690nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081174(CHEMBL3421968)copy SMILEScopy InChI
Affinity DataIC50: 779nMAssay Description:Inhibition of human recombinant N-terminal His6-tagged IGF-1R using fluorescence substrate after 80 mins by caliper off-chip incubation mobility shif...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50081193(CHEMBL3421976)copy SMILEScopy InChI
Affinity DataIC50: 810nMAssay Description:Inhibition of human full length C-terminal c-Myc tagged Dyrk1B phosphorylation overexpressed in monkey COS1 cells after 5 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61VWPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550477(CHEMBL4796479)copy SMILES
Affinity DataIC50: 810nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Homo sapiens (Human))TBA
LigandPNGBDBM50550443(CHEMBL4747823)copy SMILES
Affinity DataIC50: 860nMAssay Description:Inhibition of IDH1 R132H mutant (unknown origin) using alpha-ketoglutarate and NADPH incubated for 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73JBMPubMed
Displayed 1 to 50 (of 207 total ) | Next | Last >>
Jump to: