Compile Data Set for Download or QSAR
Found 85 with Last Name = 'cordonnier' and Initial = 'm'
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...)copy SMILES
Affinity DataIC50: 120nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...)copy SMILES
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312073(3-(6-bromo-5-fluoro- 1H-indol-3-yl)- pyrrolidine-2...)copy SMILES
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312076(3-(5-bromo-1H-indol-3- yl)pyrrolidine-2,5-dione | ...)copy SMILES
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 410nMAssay Description:Inhibition of human recombinant IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312084(3-(6-bromo-1H-indol-3- yl)pyrrolidine-2,5-dione | ...)copy SMILES
Affinity DataIC50: 420nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312072(3-(6-chloro-5-fluoro-1H- indol-3-yl)pyrrolidine- 2...)copy SMILES
Affinity DataIC50: 490nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389161((R)-3-(6-chloro-5- fluoro-1H-indol-3-yl) pyrrolidi...)copy SMILES
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312074((R)-3-(6-bromo-5- fluoro-1H-indol-3-yl)- pyrrolidi...)copy SMILES
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312069(3-(5-chloro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...)copy SMILES
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human THP1 cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389150(3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-5- carboni...)copy SMILES
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of mouse IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312088(3-(6-fluoronaphthanlen- 1-yl)pyrrolidine-2,5- dion...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human THP1 cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM389157(3-(2,5-dioxopyrrolidin- 3-yl)-1H-indole-6- carboni...)copy SMILES
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064((-)-(R)-3-(1H-indol-3- yl)pyrrolidine-2,5-dione | ...)copy SMILES
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312080(3-(5,6-difluoro-1H- indol-3-yl)pyrrolidine- 2,5-di...)copy SMILES
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312083(3-(6-chloro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312070((-)-(R)-3-(5-chloro-1H- indol-3-yl)pyrrolidine- 2,...)copy SMILES
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...)copy SMILES
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human whole blood assessed as decrease in kynurenine production after 24 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM73346(3-(1H-indol-3-yl)-2,5-pyrrolidinedione | 3-(1H-ind...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312082(3-(6-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312089(3-(7-fluoronaphthanlen- 1-yl)pyrrolidine-2,5- dion...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of IDO-1 in IFN-gamma/LPS-stimulated human whole blood assessed as decrease in kynurenine production after 24 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Mus musculus)
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310195((-)-(R)-3-(5-fluoro-1H- indol-3-yl)pyrrolidine- 2,...)copy SMILES
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of mouse IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312075(US9603836, Compound 10a | US9949951, 10a)copy SMILES
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269943(CHEMBL4073619)copy SMILEScopy InChI
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064((-)-(R)-3-(1H-indol-3- yl)pyrrolidine-2,5-dione | ...)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064((-)-(R)-3-(1H-indol-3- yl)pyrrolidine-2,5-dione | ...)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064((-)-(R)-3-(1H-indol-3- yl)pyrrolidine-2,5-dione | ...)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064((-)-(R)-3-(1H-indol-3- yl)pyrrolidine-2,5-dione | ...)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312064((-)-(R)-3-(1H-indol-3- yl)pyrrolidine-2,5-dione | ...)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310197(US10945994, Compound 2a | US9603836, Compound 2a |...)copy SMILES
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of IDO-1 in IFN-gamma-stimulated human HeLa cells assessed as decrease in kynurenine production after 16 to 24 hrs by PDMAB methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312087(3-(naphthalen-1-yl)- pyrrolidine-2,5-dione | US960...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310197(US10945994, Compound 2a | US9603836, Compound 2a |...)copy SMILES
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of human recombinant IDO-1 using tryptophan as substrate after 22 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312081(3-(5-fluoro-6-methyl- 1H-indol-3-yl)- pyrrolidine-...)copy SMILES
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269931(CHEMBL4099318)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269916(CHEMBL4098167)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269917(CHEMBL4075749)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312071(US9603836, Compound 6a | US9949951, 6a)copy SMILES
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269915(CHEMBL4080434)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM50269920(CHEMBL4065171)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312077(3-(5-methyl-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM312085(3-(6-methyl-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM310197(US10945994, Compound 2a | US9603836, Compound 2a |...)copy SMILES
Affinity DataIC50: 5.40E+4nMAssay Description:Inhibition of human recombinant IDO-1 using L-Trp as substrate after 15 mins by PDMAB-based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
iTeos Therapeutics

Curated by ChEMBL
LigandPNGBDBM309529(3-(5-fluoro-1H-indol-3- yl)pyrrolidine-2,5-dione |...)copy SMILES
Affinity DataIC50: 6.54E+4nMAssay Description:Inhibition of BCRP (unknown origin) transfected in MDCK cells assessed as decrease in pitavastatin transportMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZP48M3PubMed
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