Compile Data Set for Download or QSAR
Found 535 with Last Name = 'd''anello' and Initial = 'm'
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021624(CHEMBL3297766 | US9145418, 23)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021620(CHEMBL3297764 | US9145418, 26)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329419(5-(2-amino-5-bromopyrimidin-4-yl)-2-p-tolyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327930(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021622(CHEMBL3297767)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329420(5-(2-amino-5-chloropyrimidin-4-yl)-2-p-tolyl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327929(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329416(2-(2-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329417(5-(3-Fluoro-pyridin-4-yl)-2-phenyl-1H-pyrrole-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329418(2-Phenyl-5-pyridin-4-yl-1H-pyrrole-3-carboxamide |...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021617(CHEMBL3297761)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327928(3-({[4-(4-METHYLPIPERAZIN-1-YL)PHENYL]CARBONYL}AMI...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021649(CHEMBL3298891)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM27344(2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327923(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327927(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021653(CHEMBL3297759)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021618(CHEMBL3297762 | US9145418, 2)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of human PIM3 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021647(CHEMBL3298889)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327915(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021621(CHEMBL3297765)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329415(2-(4-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021650(CHEMBL3298892)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329426(5-(2-Amino-5-fluoro-pyrimidin-4-yl)-2-phenyl-1H-py...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327926(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of VEGFR3More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329427(5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-c...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329433(5-(2-Amino-pyrimidin-4-yl)-2-thiophen-2-yl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329414(2-(4-Methoxy-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-c...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329425(2-(3-Fluoro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-ca...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327925(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021619(CHEMBL3297763)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327924(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021618(CHEMBL3297762 | US9145418, 2)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327923(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327922(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021641(CHEMBL3298822)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327912(3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021624(CHEMBL3297766 | US9145418, 23)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of human PIM2 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329468(5-(2-Amino-pyrimidin-4-yl)-1-trifluoroethyl-2-phen...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329424(5-(2-aminopyrimidin-4-yl)-4-chloro-2-phenyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329430(5-(2-Amino-pyrimidin-4-yl)-2-thiophen-3-yl-1H-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329471(2-(2-Nitro-phenyl)-5-pyridin-4-yl-1H-pyrrole-3-car...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetCell division cycle 7-related protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM50329422(5-(2-Amino-pyrimidin-4-yl)-1-ethyl-2-phenyl-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Cdc7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6JM3PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM138348(US8877944, 99)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl

Curated by ChEMBL
LigandPNGBDBM138344(US8877944, 49)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZKFPubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50021643(CHEMBL3298886)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of human PIM1 using ARK-RERTYSFGHHA as substrate incubated for 60 mins prior to substrate addition by topcount scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4R7SPubMed
TargetAurora kinase A(Homo sapiens (Human))
Nerviano Medical Sciences-Oncology

Curated by ChEMBL
LigandPNGBDBM50327921(3-[4-(4-Methyl-piperazin-1-yl)-benzoylamino]-1H-th...)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of AurAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q240GMPubMed
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