Compile Data Set for Download or QSAR
Found 32 with Last Name = 'freschi' and Initial = 'm'
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587056(CHEMBL5080685)copy SMILES
Affinity DataIC50: 0.0352nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587059(CHEMBL5092094)copy SMILES
Affinity DataIC50: 0.177nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587057(CHEMBL5078555)copy SMILES
Affinity DataIC50: 0.265nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587057(CHEMBL5078555)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587064(CHEMBL5082773)copy SMILES
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587062(CHEMBL5084379)copy SMILES
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587066(CHEMBL5073819)copy SMILES
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587061(CHEMBL5072428)copy SMILES
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587064(CHEMBL5082773)copy SMILES
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587063(CHEMBL5077234)copy SMILES
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587058(CHEMBL5088557)copy SMILES
Affinity DataIC50: 5.70nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587055(CHEMBL5091660)copy SMILES
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587065(CHEMBL5087646)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587060(CHEMBL5078914)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587059(CHEMBL5092094)copy SMILES
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587066(CHEMBL5073819)copy SMILES
Affinity DataIC50: 19nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587061(CHEMBL5072428)copy SMILES
Affinity DataIC50: 19nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587056(CHEMBL5080685)copy SMILES
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587058(CHEMBL5088557)copy SMILES
Affinity DataIC50: 26nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587054(CHEMBL5088541)copy SMILES
Affinity DataIC50: 29nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587055(CHEMBL5091660)copy SMILES
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587054(CHEMBL5088541)copy SMILES
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587063(CHEMBL5077234)copy SMILES
Affinity DataIC50: 83nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587060(CHEMBL5078914)copy SMILES
Affinity DataIC50: 120nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587065(CHEMBL5087646)copy SMILES
Affinity DataIC50: 184nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM8987(6-chloro-1,2,3,4-tetrahydroacridin-9-amine | 6-chl...)copy SMILEScopy InChI
Affinity DataIC50: 505nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50587062(CHEMBL5084379)copy SMILES
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetAcetylcholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed
TargetCholinesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50327939(7-methoxytacrine | CHEMBL1256415)copy SMILEScopy InChI
Affinity DataIC50: 8.86E+3nMAssay Description:Inhibition of human serum BChE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VNKPubMed