Affinity DataKi: 7.40nMAssay Description:Displacement of [125I]AB-MECA from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 8.20nMAssay Description:Displacement of [125I]AB-MECA from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Affinity for A2a receptor by displacement of [3H]-CGS- 21680 from human striatumMore data for this Ligand-Target Pair
Affinity DataKi: 24nMAssay Description:Displacement of [125I]AB-MECA from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 27nMAssay Description:Binding affinity for adenosine A1 receptor of rat cerebral cortex membrane using [3H]CHAMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of [125I]AB-MECA from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 42nMAssay Description:Binding affinity for adenosine A1 receptor of rat cerebral cortex membrane using [3H]CHAMore data for this Ligand-Target Pair
Affinity DataKi: 56nMAssay Description:Displacement of [125I]AB-MECA from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 70nMAssay Description:Binding affinity for adenosine A1 receptor of rat cerebral cortex membrane using [3H]CHAMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 111nMAssay Description:Binding affinity for adenosine A1 receptor of rat cerebral cortex membrane using [3H]CHAMore data for this Ligand-Target Pair
Affinity DataKi: >200nMAssay Description:Affinity for Adenosine A1 receptor by displacement of [3H]DPCPX from human cerebral cortexMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 234nMAssay Description:Binding affinity for adenosine A1 receptor of rat cerebral cortex membrane using [3H]CHAMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 252nMAssay Description:Binding affinity for adenosine A3 receptor of rat testis membrane using [3H](R)-PIAMore data for this Ligand-Target Pair
Affinity DataKi: 381nMAssay Description:Displacement of [125I]AB-MECA from human Adenosine A3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity for adenosine A3 receptor of rat testis membrane using [3H](R)-PIAMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 1.80E+3nMAssay Description:Binding affinity for adenosine A3 receptor of rat testis membrane using [3H](R)-PIAMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Binding affinity for adenosine A3 receptor of rat testis membrane using [3H](R)-PIAMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 2.50E+3nMAssay Description:Binding affinity for adenosine A3 receptor of rat testis membrane using [3H](R)-PIAMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 3.40E+3nMAssay Description:Binding affinity for adenosine A1 receptor of rat cerebral cortex membrane using [3H]CHAMore data for this Ligand-Target Pair
Affinity DataKi: 3.48E+3nMAssay Description:Affinity for Adenosine A1 receptor by displacement of [3H]DPCPX from human cerebral cortexMore data for this Ligand-Target Pair
TargetAdenosine receptor A3(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 3.60E+3nMAssay Description:Binding affinity for adenosine A3 receptor of rat testis membrane using [3H](R)-PIAMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:Binding affinity for adenosine A2 receptor of rat striatal membrane using [3H]CGS-21680More data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 4.30E+3nMAssay Description:Binding affinity for adenosine A2 receptor of rat striatal membrane using [3H]CGS-21680More data for this Ligand-Target Pair
Affinity DataKi: 5.10E+3nMAssay Description:Affinity for A2a receptor by displacement of [3H]-CGS- 21680 from human striatumMore data for this Ligand-Target Pair
Affinity DataKi: 6.08E+3nMAssay Description:Affinity for A2a receptor by displacement of [3H]-CGS- 21680 from human striatumMore data for this Ligand-Target Pair
Affinity DataKi: 6.10E+3nMAssay Description:Affinity for A2a receptor by displacement of [3H]-CGS- 21680 from human striatumMore data for this Ligand-Target Pair
Affinity DataKi: 6.35E+3nMAssay Description:Affinity for Adenosine A1 receptor by displacement of [3H]DPCPX from human cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: 6.75E+3nMAssay Description:Affinity for A2a receptor by displacement of [3H]-CGS- 21680 from human striatumMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: 9.50E+3nMAssay Description:Binding affinity for adenosine A2 receptor of rat striatal membrane using [3H]CGS-21680More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for A2a receptor by displacement of [3H]-CGS- 21680 from human striatumMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for Adenosine A1 receptor by displacement of [3H]DPCPX from human cerebral cortexMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for Adenosine A1 receptor by displacement of [3H]DPCPX from human cerebral cortexMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for adenosine A2 receptor of rat striatal membrane using [3H]CGS-21680More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Affinity for Adenosine A1 receptor by displacement of [3H]DPCPX from human cerebral cortexMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for adenosine A2 receptor of rat striatal membrane using [3H]CGS-21680More data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
GlaxoWellcome Medicines Research Center
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity for adenosine A2 receptor of rat striatal membrane using [3H]CGS-21680More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of human NEP-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant mGluR1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human ACE-mediated amyloid beta hydrolysisMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant mGluR1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant mGluR1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant mGluR1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant mGluR1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant mGluR1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of recombinant mGluR1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant mGluR1a receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant IDE-mediated amyloid beta (16 to 23) hydrolysis using ATTO 655-Cys-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Trp as substrate p...More data for this Ligand-Target Pair
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