Found 124 with Last Name = 'ishizawa' and Initial = 'm' 
Affinity DataKi: 1.30E+3nM ΔG°: -34.9kJ/mole IC50: 800nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nM ΔG°: -33.0kJ/mole IC50: 900nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataKi: 5.20E+3nM ΔG°: -31.4kJ/mole IC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 0.0500nMAssay Description:Transrepression of VP16-tagged VDR (unknown origin) expressed in HEK293 cells harboring pCMX-GAL4-NCoR and MH100(UAS) X 4tk-LUC reporter plasmid asse...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Transrepression of VP16-tagged VDR (unknown origin) expressed in HEK293 cells harboring pCMX-GAL4-NCoR and MH100(UAS) X 4tk-LUC reporter plasmid asse...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 0.0900nMAssay Description:Agonist activity at VDR (unknown origin) expressed in HEK293 cells cotransfected with NCoR assessed as decrease in NCoR recruitment by two-hybrid ass...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Agonist activity at VDR (unknown origin) expressed in HEK293 cells cotransfected with NCoR assessed as decrease in NCoR recruitment by two-hybrid ass...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Displacement of [26,27-Methyl-3H]-1,25(OH)2D3 from recombinant human GST-tagged VDR LBD (140 to 427 residues) expressed in Escherichia coli BL21 prei...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 0.350nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from recombinant human VDR ligand binding domainMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Transrepression of VP16-tagged VDR (unknown origin) expressed in HEK293 cells harboring pCMX-GAL4-NCoR and MH100(UAS) X 4tk-LUC reporter plasmid asse...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Displacement of [26,27-Methyl-3H]-1,25(OH)2D3 from recombinant human GST-tagged VDR LBD (140 to 427 residues) expressed in Escherichia coli BL21 prei...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from recombinant human VDR ligand binding domainMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from GST-fused human VDR-LBD expressed in Escherichia coli BL21More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from recombinant human VDR ligand binding domainMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from recombinant human VDR ligand binding domainMore data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Displacement of [3H]-1,25(OH)2D3 from recombinant human VDR ligand binding domainMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataIC50: 1.83E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:Briefly, Bc-SMase (50 ng/ml) was treated at 37 °C for 60 min with various compounds that were solubilized in dimethylacetoamide. The reaction mix...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 6.60nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 1.10nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 0.0700nMAssay Description:Transactivation of human VDR expressed in HEK293 cells cotransfected with mouse VDRE, Tk-Sppx3-LUC reporter plasmid measured after 24 hrs by lucifera...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 4.40nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 0.600nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 2.30nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 0.800nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-RXRalpha and 4-tk-LUC assessed as heterodimerization with RXRalpha by mammal...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 1.5nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 6.5nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 14nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-SRC1 and 4-tk-LUC assessed as SRC1 interaction with AF2 surface of VDR by ma...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 0.400nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 3.70nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 1.80nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-N-CoR and 4-tk-LUC assessed as inhibition of N-CoR binding to VDR by mammali...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 4.10nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 0.5nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 2.40nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
TargetVitamin D3 receptor(Homo sapiens (Human))
Universidad de Santiago de Compostela
Curated by ChEMBL
Universidad de Santiago de Compostela
Curated by ChEMBL
Affinity DataEC50: 2.80nMAssay Description:Activation of human VDR expressed in HEK293 cells cotransfected CMX-GAL4-NCoR2 and 4-tk-LUC assessed as inhibition of NCoR2 binding to VDR by mammali...More data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University of Tokyo
Curated by ChEMBL
University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 3.60E+3nMAssay Description:Effect on PPARgamma transactivation activity in HEK293 cellsMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
University of Tokyo
Curated by ChEMBL
University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 650nMAssay Description:Effect on PPARgamma transactivation activity in HEK293 cellsMore data for this Ligand-Target Pair
