TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 79nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibitory activity was assessed under the following conditions: 350 uM ATP/1.5 ug mL−1 RNA indicated by black; 35 uM ATP/1.5 ug mL−1 RNA...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 280nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 490nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 580nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 830nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 helicase activity expressed in baculovirus infected Sf9 cells assessed as redu...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity was assessed under the following conditions: 350 uM ATP/1.5 ug mL−1 RNA indicated by black; 35 uM ATP/1.5 ug mL−1 RNA...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of MLN51-induced full length recombinant human N-terminal His6/SUMO-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia c...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.
Curated by ChEMBL
Takeda California Inc.
Curated by ChEMBL
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair
TargetEukaryotic initiation factor 4A-III(Homo sapiens (Human))
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Takeda Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MLN51-induced full-length human recombinant His6-tagged eIF4A3 RNA dependent ATPase activity expressed in Escherichia coli BL21(DE3) us...More data for this Ligand-Target Pair