Found 74 with Last Name = 'jeske' and Initial = 'm' TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 7.05nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 11.1nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 11.1nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 14.6nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 15.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 15.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 17.0nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 17.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 18.4nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 19.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 21.3nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 25nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 29nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 33.6nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 53.7nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 70nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 79.9nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 90nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 98.2nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 109nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 109nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 130nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 165nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 170nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 180nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 237nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 248nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 260nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Affinity DataIC50: 340nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 359nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 360nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 380nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 480nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
TargetProteinase-activated receptor 1(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 483nMpH: 7.5 T: 2°CAssay Description:Platelet membranes are incubated with 12 nM [3H]haTRAP and test substance in different concentrations in a buffer (50 mM Tris pH 7.5, 10 mM magnesium...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 540nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
Affinity DataIC50: 560nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 690nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Affinity DataIC50: 740nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
Affinity DataIC50: 750nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))
Bayer Intellectual Property GmbH
US Patent
Bayer Intellectual Property GmbH
US Patent
Affinity DataIC50: 760nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
Affinity DataIC50: 780nMAssay Description:Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...More data for this Ligand-Target Pair
