Found 80 with Last Name = 'kokot' and Initial = 'm' Target85/88 kDa calcium-independent phospholipase A2(Homo sapiens (Human))
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant G6A iPLA2 using arachidonyl-1-14C PAPC and PAPC incubated for 30 mins by HPLC-MS analysis based radioactivity-based g...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.70nMAssay Description:Inhibition of recombinant mouse ATX expressed in HEK293 cells using LPC 17:0 as substrate after 30 mins by LC-MS/MS methodMore data for this Ligand-Target Pair
3D Structure (crystal)TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 2.80nMAssay Description:Inhibition of recombinant mouse ATX expressed in HEK293 cells using FS3 as substrate preincubated for 15 mins followed by substrate addition measured...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 35nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 67nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 87nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 101nMAssay Description:Inhibition of ATX in human whole blood assessed as decrease in LPA levels after 2 hrs by LC-MS/MS methodMore data for this Ligand-Target Pair
Affinity DataIC50: 123nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 172nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 197nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 215nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 236nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 241nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 244nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 283nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 326nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 356nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 374nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of mouse ATX-beta using LPC 18:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 570nMAssay Description:Inhibition of Escherichia coli DNA gyrase assessed as reduction in DNA supercoiling using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 725nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of Staphylococcus aureus topoisomerase 4 assessed as reduction in decatenation using supercoiled pNO1 plasmid DNA as substrate incubated f...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
National and Kapodistrian University of Athens
Curated by ChEMBL
National and Kapodistrian University of Athens
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of mouse ATX-beta using LPC 16:0 as substrate by Amplex Red PLD assayMore data for this Ligand-Target Pair
