Compile Data Set for Download or QSAR
Found 134 with Last Name = 'kothare' and Initial = 'm'
LigandPNGBDBM24198(3-aminopropylphosphinic derivative, (R)-8 | [(2R)-...)copy SMILEScopy InChI
Affinity DataKi:  4.30nM ΔG°:  -47.3kJ/mole EC50:  14nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24195(3-aminopropylphosphinic derivative, (R)-7 | AZD335...)copy SMILEScopy InChI
Affinity DataKi:  5.10nM ΔG°:  -46.9kJ/mole EC50:  8.64nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24193((3-amino-2-fluoropropyl)phosphinic acid | 3-aminop...)copy SMILEScopy InChI
Affinity DataKi:  10nM ΔG°:  -45.2kJ/mole EC50:  15nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24196((3-amino-2-fluoropropyl)(methyl)phosphinic acid | ...)copy SMILEScopy InChI
Affinity DataKi:  14nM ΔG°:  -44.4kJ/mole EC50:  23nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24184((3-aminopropyl)phosphinic acid | 3-aminopropylphos...)copy SMILEScopy InChI
Affinity DataKi:  15nM ΔG°:  -44.2kJ/mole EC50:  19nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24185((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)copy SMILEScopy InChI
Affinity DataKi:  33nM ΔG°:  -42.3kJ/mole EC50:  41nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
LigandPNGBDBM24191((3-amino-2-oxopropyl)phosphinic acid | (3-amino-2-...)copy SMILEScopy InChI
Affinity DataKi:  48nM ΔG°:  -41.4kJ/mole EC50:  81nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)copy SMILEScopy InChI
Affinity DataKi:  50nM ΔG°:  -41.3kJ/mole EC50:  130nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24194(3-aminopropylphosphinic derivative, (S)-7 | [(2S)-...)copy SMILEScopy InChI
Affinity DataKi:  70nM ΔG°:  -40.4kJ/mole EC50:  250nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)copy SMILEScopy InChI
Affinity DataKi:  94nM ΔG°:  -39.7kJ/mole EC50:  220nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)copy SMILEScopy InChI
Affinity DataKi:  180nM ΔG°:  -38.1kJ/mole EC50:  150nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24192((3-amino-2-oxopropyl)(methyl)phosphinic acid | (3-...)copy SMILEScopy InChI
Affinity DataKi:  200nM ΔG°:  -37.9kJ/mole EC50:  270nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)copy SMILEScopy InChI
Affinity DataKi:  220nM ΔG°:  -37.6kJ/mole EC50:  750nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
LigandPNGBDBM24197(3-aminopropylphosphinic derivative, (S)-8 | [(2S)-...)copy SMILEScopy InChI
Affinity DataKi:  480nM ΔG°:  -35.7kJ/mole EC50:  1.70E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24189(3-aminopropylphosphinic derivative, (R)-4 | 3-amin...)copy SMILEScopy InChI
Affinity DataKi:  840nM ΔG°:  -34.3kJ/mole EC50:  600nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
LigandPNGBDBM24186((3-amino-2-hydroxypropyl)phosphinic acid | 3-amino...)copy SMILEScopy InChI
Affinity DataKi:  2.10E+3nM ΔG°:  -32.1kJ/mole EC50:  1.10E+3nMpH: 7.4 T: 2°CAssay Description:Inhibition of [3H]GABA binding at GABAB receptor sites in rat brain synaptic membranes by test compounds was measured using a filtration binding assa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32T2TPubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50067584((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)copy SMILEScopy InChI
Affinity DataIC50: 0.610nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22F7MQ7PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033553(6-{[Methyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033547(6-[(2,6-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033555(6-{[Prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amino]-m...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033557(6-{[(2,5-Dimethoxy-phenyl)-methyl-amino]-methyl}-5...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033556(6-{[(2,5-Dimethoxy-phenyl)-ethyl-amino]-methyl}-5,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033550(6-{[(2,5-Diethoxy-phenyl)-methyl-amino]-methyl}-5,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50108065(4'-(2-Amino-3-mercapto-propylamino)-[1,1';2',1'']t...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22F7MQ7PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033546(6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-5,...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033543(6-{[(4-Chloro-phenyl)-methyl-amino]-methyl}-5,6,7,...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033552(6-(2,3-Dihydro-indol-1-ylmethyl)-5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50108067(2-Amino-3-[3'-(5H-tetrazol-5-yl)-biphenyl-4-ylamin...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22F7MQ7PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033540(6-[(3-Bromo-phenylamino)-methyl]-5,6,7,8-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033546(6-{[(3,4-Dichloro-phenyl)-methyl-amino]-methyl}-5,...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033542(6-(Naphthalen-1-ylaminomethyl)-5,6,7,8-tetrahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondiiMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50048961(4'-((R)-2-Amino-3-mercapto-propylamino)-2'-methoxy...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22F7MQ7PubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033553(6-{[Methyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDimer of Protein farnesyltransferase subunit beta(Homo sapiens (Human))
Yale University

Curated by ChEMBL
LigandPNGBDBM50108058(4'-(2-Amino-3-mercapto-propylamino)-2'-propoxy-bip...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of farnesyltransferase from human Burkitt lymphoma (Daudi) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22F7MQ7PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM18268(5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}...)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033539(6-[(3,4,5-Trimethoxy-phenylamino)-methyl]-5,6,7,8-...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033543(6-{[(4-Chloro-phenyl)-methyl-amino]-methyl}-5,6,7,...)copy SMILEScopy InChI
Affinity DataIC50: 67nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033556(6-{[(2,5-Dimethoxy-phenyl)-ethyl-amino]-methyl}-5,...)copy SMILEScopy InChI
Affinity DataIC50: 71nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033555(6-{[Prop-2-ynyl-(3,4,5-trimethoxy-phenyl)-amino]-m...)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033545(6-[(4-Chloro-phenylamino)-methyl]-5,6,7,8-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033553(6-{[Methyl-(3,4,5-trimethoxy-phenyl)-amino]-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 95nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033554(6-[(2,5-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033544(6-[(Methyl-naphthalen-1-yl-amino)-methyl]-5,6,7,8-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033547(6-[(2,6-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 109nMAssay Description:Inhibitory activity against purified DHFR (Dihydrofolate reductase) from ratMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033541(6-[(3,4-Dichloro-phenylamino)-methyl]-5,6,7,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibitory activity against purified Dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50033556(6-{[(2,5-Dimethoxy-phenyl)-ethyl-amino]-methyl}-5,...)copy SMILEScopy InChI
Affinity DataIC50: 114nMAssay Description:Inhibitory activity against purified dihydrofolate reductase from Pneumocystis carinii.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27080FNPubMed
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