Compile Data Set for Download or QSAR
Found 36 with Last Name = 'kuzma' and Initial = 'm'
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM50366800(OLOMOUCINE II)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132192(CHEMBL102871 | N*2*-(4-Amino-cyclohexyl)-N*6*-(3-c...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Palacky£? University and Institute of Experimental Botany ASCR

Curated by ChEMBL
LigandPNGBDBM50341878((2R)-2-{[7-(benzylamino)-3-(propan-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant CDK2/cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28XNPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM10642(2-[({2-[(1-hydroxy-3-methylbutan-2-yl)amino]-9-(pr...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM50120508(2-(3-hydroxypropylamino)-6-(o -hydroxybenzylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM10635(3-[({2-[(1-hydroxy-3-methylbutan-2-yl)amino]-9-(pr...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM50120510(4-{[2-(1-Hydroxymethyl-2-methyl-propylamino)-9-iso...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Palacky£? University and Institute of Experimental Botany ASCR

Curated by ChEMBL
LigandPNGBDBM50341878((2R)-2-{[7-(benzylamino)-3-(propan-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant CDK7/cyclin H/MAT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28XNPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM50120512(3-{[2-(1-Hydroxymethyl-propylamino)-9-isopropyl-9H...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Palacky£? University and Institute of Experimental Botany ASCR

Curated by ChEMBL
LigandPNGBDBM50341878((2R)-2-{[7-(benzylamino)-3-(propan-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5/p35More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28XNPubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Palacky£? University and Institute of Experimental Botany ASCR

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant CDK2/cyclin EMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM50120507(4-{[2-(1-Hydroxymethyl-propylamino)-9-isopropyl-9H...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Palacky£? University and Institute of Experimental Botany ASCR

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of human recombinant CDK7/cyclin H/MAT1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28XNPubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Palacky£? University and Institute of Experimental Botany ASCR

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of human recombinant CDK5/p35More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Palacky£? University and Institute of Experimental Botany ASCR

Curated by ChEMBL
LigandPNGBDBM50341878((2R)-2-{[7-(benzylamino)-3-(propan-2-yl)-1H-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant CDK9/cyclin T1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28XNPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM50120509(3-{[2-(3-Hydroxy-propylamino)-9-isopropyl-9H-purin...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM10633(3-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Palacky£? University and Institute of Experimental Botany ASCR

Curated by ChEMBL
LigandPNGBDBM7533((2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]am...)copy SMILEScopy InChI
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of human recombinant CDK9/cyclin T1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K28XNPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM50120511(4-{[2-(3-Hydroxy-propylamino)-9-isopropyl-9H-purin...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132199(3-{[8-Chloro-2-(1-hydroxymethyl-propylamino)-9-iso...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3(Homo sapiens (Human))
Palack£ University and Institute of Experimental Botany

Curated by ChEMBL
LigandPNGBDBM5718(2,6,9-Trisubstituted purine deriv. 26 | 2-{[6-(ben...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8MK1PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132196(2-(6-Benzylamino-9-isopropyl-8-methyl-9H-purin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132197(2-(6-Benzylamino-9-isopropyl-8-mercapto-9H-purin-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132193(2-[8-Chloro-6-(3-chloro-phenylamino)-9-isopropyl-9...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132198(CHEMBL103567 | N*2*-(4-Amino-cyclohexyl)-N*6*-(3-c...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132189(2-(6-Benzylamino-9-isopropyl-8-nitro-9H-purin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132190(2-(6-Benzylamino-8-chloro-9-isopropyl-9H-purin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132195(6-Benzylamino-2-(1-hydroxymethyl-propylamino)-9-is...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132188(2-(8-Amino-6-benzylamino-9-isopropyl-9H-purin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132194(2-[6-Benzylamino-8-(3-hydroxy-propylamino)-9-isopr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132200(2-(6-Benzylamino-9-isopropyl-8-propoxy-9H-purin-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Academy of Sciences of the Czech Republic

Curated by ChEMBL
LigandPNGBDBM50132191(2-(6-Benzylamino-8-bromo-9-isopropyl-9H-purin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Cyclin dependent kinase 1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q270820NPubMed