Found 106 with Last Name = 'laiho' and Initial = 'm' TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 210nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 420nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 470nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 660nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 740nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 920nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 990nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.09E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.25E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.35E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.39E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assayMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.01E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human hepatic CYP1A2 expressed in baculovirus insect cell expression system in presence of CEC substrate measured by fluore...More data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 2.17E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
TargetDNA-directed RNA polymerase I subunit RPA1(Homo sapiens (Human))
Johns Hopkins University School of Medicine
Curated by ChEMBL
Johns Hopkins University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 3.04E+3nMAssay Description:Induction of RNA polymerase-1 RPA194 subunit degradation in human U2OS cells after 3 hrs by epifluorescence microscopic analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 3.64E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.72E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition on hERG expressed in HEK293 cells by Qpatch methodMore data for this Ligand-Target Pair
