Compile Data Set for Download or QSAR
Found 100 with Last Name = 'mccleland' and Initial = 'm'
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50265275(4-(4-iodophenoxy)-2-(2H-tetrazol-5-yl)thieno[2,3-c...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169081(CHEMBL3806220)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50265311(4-(4-chlorophenoxy)-2-(2H-tetrazol-5-yl)thieno[2,3...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169082(CHEMBL3805960)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169062(CHEMBL3805194)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50265309(2-(2H-tetrazol-5-yl)-4-(p-tolyloxy)thieno[2,3-c]py...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169080(CHEMBL3806173)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169078(CHEMBL3804919)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50264866(4'-(2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin-4-ylo...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetL-lactate dehydrogenase A chain(Homo sapiens (Human))
Genentech

LigandPNGBDBM197160(GNE-140 (6))copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532620(CHEMBL4440347)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532620(CHEMBL4440347)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169079(CHEMBL3805857)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

LigandPNGBDBM197160(GNE-140 (6))copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95800PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50105215(4-(4-Cyano-phenoxy)-thieno[2,3-c]pyridine-2-carbox...)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169071(CHEMBL3806024)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169083(CHEMBL3805667)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50105170(4-p-Tolyloxy-thieno[2,3-c]pyridine-2-carboxylic ac...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50105181(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 6.20nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169064(CHEMBL3806134)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50105159(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50265277(4-phenoxy-2-(2H-tetrazol-5-yl)thieno[2,3-c]pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532615(CHEMBL4549408)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532615(CHEMBL4549408)copy SMILEScopy InChI
Affinity DataIC50: 8.90nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532614(CHEMBL4566932)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532614(CHEMBL4566932)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169067(CHEMBL3805684)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169070(CHEMBL3806182)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532619(CHEMBL4568245)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532628(CHEMBL4461493)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532619(CHEMBL4568245)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532628(CHEMBL4461493)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50105153(4-(4-Chloro-phenoxy)-thieno[2,3-c]pyridine-2-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169068(CHEMBL3806291)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532616(CHEMBL4532382)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532616(CHEMBL4532382)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532623(CHEMBL4530828)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532623(CHEMBL4530828)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532622(CHEMBL4581368)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532622(CHEMBL4581368)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532627(CHEMBL4514427)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169069(CHEMBL3806265)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50532627(CHEMBL4514427)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XG9VN3PubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169076(CHEMBL3806114)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50105218(4-(4-Methoxy-phenoxy)-thieno[2,3-c]pyridine-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50105206(4-(4-Acetylamino-phenoxy)-thieno[2,3-c]pyridine-2-...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169073(CHEMBL3805204)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM50169074(CHEMBL3806037)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of full length human recombinant His-tagged CDK8/Cyclin C expressed in baculovirus expression system by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29G5PPCPubMed
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
TargetCyclin-C(Homo sapiens (Human))
Genentech, Inc

Curated by ChEMBL
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Displacement of tracer236 from full-length His-tagged CDK8/cyclin C (unknown origin) incubated for 1 hr by TR-FRET analysisMore data for this Ligand-Target Pair
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