Compile Data Set for Download or QSAR
Found 210 with Last Name = 'mcphillie' and Initial = 'm'
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))TBA
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.254nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.259nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 0.370nMMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))TBA
LigandPNGBDBM185674(4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 0.75nMMore data for this Ligand-Target Pair
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))TBA
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)copy SMILEScopy InChI
TargetNT-3 growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM185149(1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetALK tyrosine kinase receptor(Homo sapiens (Human))TBA
LigandPNGBDBM158154(US10081622, Compound 11 | US10370379, Entrectinib ...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM185674(4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)ca...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM185149(1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50174768(5‐chloro‐2‐(2‐chloro‐...)copy SMILEScopy InChI
Affinity DataIC50: 3nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetNT-3 growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))TBA
LigandPNGBDBM136597(US10005783, 14 | US10047097, 14 | US10774085, Exam...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM185674(4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)ca...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM185149(1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM25407(2‐(2,4‐dichlorophenoxy)‐5‐...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50174760(2‐[4‐(benzylamino)‐2‐chlor...)copy SMILEScopy InChI
Affinity DataIC50: 13nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM8726(5-chloro-2-(2,4-dichlorophenoxy)phenol | CHEMBL849...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of Toxoplasma gondii enoyl acyl-carrier protein reductaseMore data for this Ligand-Target Pair
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50174774(2‐({[3‐chloro‐4‐(4‐c...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM119865(6‐chloro‐3‐(2,4‐dichloroph...)copy SMILEScopy InChI
Affinity DataIC50: 18nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50435717(CHEMBL2392450 | N‐{[4‐(2,4‐dichl...)copy SMILEScopy InChI
Affinity DataIC50: 19nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50435717(CHEMBL2392450 | N‐{[4‐(2,4‐dichl...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:Inhibition of Toxoplasma gondii enoyl acyl-carrier protein reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GZ7PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM119866(3‐chloro‐6‐(2,4‐dichloroph...)copy SMILEScopy InChI
Affinity DataIC50: 23nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM25403(4‐(2,4‐dichlorophenoxy)‐3‐...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50596395(CHEMBL5196221)copy SMILES
Affinity DataIC50: 24nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM119867(5‐chloro‐2‐[2‐chloro‐...)copy SMILEScopy InChI
Affinity DataIC50: 26nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50435720(CHEMBL2392447)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of Toxoplasma gondii enoyl acyl-carrier protein reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GZ7PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50431922(5‐chloro‐2‐[2‐chloro‐...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM119869(5‐chloro‐2‐{2‐chloro‐...)copy SMILEScopy InChI
Affinity DataIC50: 31nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM119870(N‐{[3‐chloro‐4‐(4‐ch...)copy SMILEScopy InChI
Affinity DataIC50: 33nMpH: 7.5Assay Description:The reaction mixture (100 µL) contained 100 µM crotonyl-CoA, 1 µL DMSO (or compounds dissolved in DMSO), 5 nM TgENR, 100 mM sodium/pot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6J27PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6HXNPubMed
TargetEnoyl-acyl carrier reductase ENR(Toxoplasma gondii)
Johns Hopkins Bloomberg School of Public Health

LigandPNGBDBM50435719(CHEMBL2392448)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of Toxoplasma gondii enoyl acyl-carrier protein reductaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8GZ7PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50315887((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Compound was tested for the biological activity at the Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
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