Compile Data Set for Download or QSAR
Found 23 with Last Name = 'nautiyal' and Initial = 'm'
TargetAspartate--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50339907(((S)-2-amino-3-carboxypropanoyl)(((2R,3S,4R,5R)-5-...)copy SMILEScopy InChI
Affinity DataKi:  0.0520nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Aspartyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheric...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458119(Leusa)copy SMILEScopy InChI
Affinity DataKi:  0.139nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichi...More data for this Ligand-Target Pair
TargetSerine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50339906(((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihyd...)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Seryl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichia...More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458122(CHEMBL4204314)copy SMILEScopy InChI
Affinity DataKi:  0.654nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Leucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524451(CHEMBL4553017)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B73PubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50222902(CHEMBL1163069)copy SMILEScopy InChI
Affinity DataKi:  1.90nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheri...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458121(CHEMBL1163085)copy SMILEScopy InChI
Affinity DataKi:  2.90nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Tyrosyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherich...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524359(CHEMBL4465674)copy SMILEScopy InChI
Affinity DataKi:  9.80nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524360(CHEMBL3265242)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524355(CHEMBL4467328)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetAspartate--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458117(CHEMBL4203761)copy SMILEScopy InChI
Affinity DataKi:  25nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Aspartyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheric...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458118(CHEMBL4208126)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Tyrosyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherich...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetLeucine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524361(CHEMBL4451258)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) leuRS incubated for 10 mins in presence of 14C-labeled leucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524357(CHEMBL4558119)copy SMILEScopy InChI
Affinity DataKi:  43nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524354(CHEMBL3265243)copy SMILEScopy InChI
Affinity DataKi:  55nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50544145(CHEMBL4636583)copy SMILEScopy InChI
Affinity DataKi:  88nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K4QPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50544146(CHEMBL4648043)copy SMILEScopy InChI
Affinity DataKi:  114nMAssay Description:Inhibition of Escherichia coli BL21(DE3) ileRS overexpressed in Escherichia coli Rosetta2(DE3) assessed as reduction in tRNA aminoacylation preincuba...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8K4QPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524353(CHEMBL4518549)copy SMILEScopy InChI
Affinity DataKi:  149nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458120(CHEMBL4215986)copy SMILEScopy InChI
Affinity DataKi:  213nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Isoleucyl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escheri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetSerine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50458116(CHEMBL4208640)copy SMILEScopy InChI
Affinity DataKi:  523nMAssay Description:Inhibition of Escherichia coli BL21(DE3) Seryl-tRNA synthetase assessed as reduction in tRNA aminoacylation preincubated for 10 mins with Escherichia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2057JJSPubMed
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524358(CHEMBL4475568)copy SMILEScopy InChI
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) ileRS incubated for 10 mins in presence of 14C-labeled isoleucine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0CCGPubMed
TargetTyrosine--tRNA ligase(Escherichia coli (strain K12))
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524356(CHEMBL4460886)copy SMILEScopy InChI
Affinity DataKi:  1.48E+3nMAssay Description:Inhibition of purified Escherichia coli BL21 (DE3) tyrRS incubated for 10 mins in presence of 14C-labeled tyrosine by radiolabel transfer assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetIsoleucine--tRNA ligase(Escherichia coli)
KU Leuven

Curated by ChEMBL
LigandPNGBDBM50524451(CHEMBL4553017)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:Inhibition of recombinant Escherichia coli BL21(DE3) isoleucyl-tRNA synthetase expressed in Escherichia coli Rosetta 2 (DE3) assessed as reduction in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M3B73PubMed