TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 56nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 88nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 131nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 137nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 204nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 460nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 579nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Innsbruck Medical University
Curated by ChEMBL
Innsbruck Medical University
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of recombinant PKCepsilon (unknown origin)-MBP-tagged RACK2 interaction after 1 hr by ELISA-based assay relative to untreated controlMore data for this Ligand-Target Pair
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Innsbruck Medical University
Curated by ChEMBL
Innsbruck Medical University
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of recombinant PKCepsilon (unknown origin)-MBP-tagged RACK2 interaction after 1 hr by ELISA-based assay relative to untreated controlMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human EPHB4More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human INSRMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human CDK4/CycD1More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human SRCMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human EPHB4More data for this Ligand-Target Pair
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Gause Institute of New Antibiotics
Curated by ChEMBL
Gause Institute of New Antibiotics
Curated by ChEMBL
Affinity DataIC50: 3.93E+3nMAssay Description:Inhibition of human recombinant SIRT1 deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC as substrate incubated for 45 mins by fluorescen...More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human IGF1RMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human PDGFRbetaMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human CDK2/Cyc2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human AXLMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Aventis Pharmaceuticals
Curated by ChEMBL
Aventis Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of K+ channel activity in CHO cells expressing HERG Kv11.1More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human EGFRMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Institute of General Genetics
Curated by ChEMBL
Institute of General Genetics
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
TargetAurora kinase B(Homo sapiens (Human))
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human N-terminal GST-HIS6-tagged Aurora B expressed in sf9 cells by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human N-terminal GST-HIS6-tagged PIM1 expressed in sf9 cells by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-3(Homo sapiens (Human))
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length human N-terminal GST-HIS6-tagged PIM3 expressed in sf9 cells by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 7(Homo sapiens (Human))
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MAP3K7 by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
TargetDual serine/threonine and tyrosine protein kinase(Homo sapiens (Human))
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Russia; Mendeleyev University of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human RIPK5 by flashplate based radiometric 33pan-quinase assayMore data for this Ligand-Target Pair
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