Compile Data Set for Download or QSAR
Found 33 with Last Name = 'rodriquez-lens' and Initial = 'm'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297795(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297794(2-(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297796(4-(cyclohexylmethyl)-6-(2-methoxypyrimidin-5-yl)-2...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297797(4-(cyclohexylmethyl)-6-(6-methoxypyridin-3-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297798(4-(cyclohexylmethyl)-6-(pyridin-4-yl)-2-((tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297799(4-(cyclohexylmethyl)-6-(3,5-dimethylisoxazol-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297800(6-(4-fluorophenyl)-4-(4-methoxybenzyl)-2-(2-morpho...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297801(4-(cyclohexylmethyl)-6-(3,4-difluorophenyl)-2-(2-m...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297802(6-(3,4-difluorophenyl)-4-(4-methoxybenzyl)-2-(2-mo...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297803(6-(6-methoxypyridin-3-yl)-4-(2-propoxyethyl)-2-((t...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50296252(6-(6-methoxypyridin-3-yl)-2-(2-morpholinoethylamin...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297804(6-(4-fluorophenyl)-4-(pyridin-3-ylmethyl)-2-((tetr...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297805(4-(3,5-difluorobenzyl)-6-(4-fluorophenyl)-2-((tetr...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297806(4-(cyclohexylmethyl)-6-(6-hydroxypyridin-3-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297807(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-((tetrah...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297808(2-(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-3-oxo-3...)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297809(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-(2-morph...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297810(4-(cyclohexylmethyl)-6-(4-fluorophenyl)-2-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297811(2-(6-(6-methoxypyridin-3-yl)-3-oxo-4-(2-propoxyeth...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297812(6-(4-fluorophenyl)-4-(pyridin-2-ylmethyl)-2-((tetr...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297813(6-(4-fluorophenyl)-4-(2-propoxyethyl)-2-((tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297793(1-(4-methoxybenzyl)-7-(pyridin-4-yl)quinolin-2(1H)...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297814(6-(2-methoxypyrimidin-5-yl)-2-(2-morpholinoethylam...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297815(2-amino-4-(cyclohexylmethyl)-6-(4-fluorophenyl)pyr...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297816(6-(4-fluorophenyl)-2-(2-morpholinoethylamino)-4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297817(4-(2-propoxyethyl)-6-(pyridin-4-yl)-2-((tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297818(6-(3,5-dimethylisoxazol-4-yl)-2-(2-morpholinoethyl...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297792(7-(3,4-difluorophenyl)-4-methyl-1-pentyl-3,4-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297791(5-amino-7-phenyl-1-propyl-1,6-naphthyridin-4(1H)-o...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297819(6-(3,4-difluorophenyl)-4-(2-isopropoxyethyl)-2-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297820(4-(2-ethoxyethyl)-6-(4-fluorophenyl)-2-((tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 149nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297821(6-(4-fluorophenyl)-4-isobutyl-2-((tetrahydro-2H-py...)copy SMILEScopy InChI
Affinity DataIC50: 224nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50297822(6-(6-hydroxypyridin-3-yl)-2-(2-morpholinoethylamin...)copy SMILEScopy InChI
Affinity DataIC50: 534nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0SXRPubMed