Compile Data Set for Download or QSAR
Found 57 with Last Name = 'sadiq' and Initial = 'm'
LigandPNGBDBM50585957(CHEMBL5076191)copy SMILES
Affinity DataKi:  240nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 using 4-NBA and NADP+ as substrate by Michaelis-Menten based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
LigandPNGBDBM50585956(CHEMBL5082977)copy SMILES
Affinity DataKi:  300nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 using 4-NBA and NADP+ as substrate by Michaelis-Menten based analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585949(CHEMBL5083058)copy SMILES
Affinity DataKi:  460nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as increase in Km without change in Vmax using hexanal as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585950(CHEMBL5075900)copy SMILES
Affinity DataKi: <1.00E+3nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as increase in Km without change in Vmax using hexanal as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585951(CHEMBL5086460)copy SMILES
Affinity DataKi: <1.00E+3nMAssay Description:Competitive inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as increase in Km without change in Vmax using hexanal as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585950(CHEMBL5075900)copy SMILES
Affinity DataIC50: 260nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM69358(3-nitro-4-(1-pyrrolidinyl)benzaldehyde | 3-nitro-4...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585951(CHEMBL5086460)copy SMILES
Affinity DataIC50: 300nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585952(CHEMBL5090970)copy SMILES
Affinity DataIC50: 310nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of AKR1C3 (unknown origin) using S-tetralol as substrate in presence of NADP+ by fluorimteryMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of type-1 human steroid 5-alpha-reductaseMore data for this Ligand-Target Pair
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))TBA
LigandPNGBDBM50076742(CHEBI:86194 | CHEMBL3416563)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A1 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50278013(CHEMBL4166887)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585953(CHEMBL5087589)copy SMILES
Affinity DataIC50: 550nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)copy SMILEScopy InChI
Affinity DataIC50: 610nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585949(CHEMBL5083058)copy SMILES
Affinity DataIC50: 630nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))TBA
LigandPNGBDBM50585947(CHEMBL5093301)copy SMILES
Affinity DataIC50: 800nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A1 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))TBA
LigandPNGBDBM50585948(CHEMBL5083538)copy SMILES
Affinity DataIC50: 880nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A1 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585947(CHEMBL5093301)copy SMILES
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
LigandPNGBDBM50585957(CHEMBL5076191)copy SMILES
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277997(CHEMBL4159654)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
LigandPNGBDBM50585956(CHEMBL5082977)copy SMILES
Affinity DataIC50: 1.61E+3nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585954(CHEMBL5092526)copy SMILES
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM22369(4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofu...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)copy SMILEScopy InChI
Affinity DataIC50: 3.56E+3nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585948(CHEMBL5083538)copy SMILES
Affinity DataIC50: 4.86E+3nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
LigandPNGBDBM50076742(CHEBI:86194 | CHEMBL3416563)copy SMILEScopy InChI
Affinity DataIC50: 5.67E+3nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase 1A1(Homo sapiens (Human))TBA
LigandPNGBDBM50585949(CHEMBL5083058)copy SMILES
Affinity DataIC50: 7.08E+3nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A1 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
LigandPNGBDBM50585949(CHEMBL5083058)copy SMILES
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 8.63E+3nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50278013(CHEMBL4166887)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50076742(CHEBI:86194 | CHEMBL3416563)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldehyde dehydrogenase family 1 member A3(Homo sapiens (Human))TBA
LigandPNGBDBM50585955(CHEMBL5093580)copy SMILES
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH1A3 assessed as reduction in NADH production using hexanal and NAD+ as substrate by fluori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277997(CHEMBL4159654)copy SMILEScopy InChI
Affinity DataIC50: 1.32E+4nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
LigandPNGBDBM50585953(CHEMBL5087589)copy SMILES
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University of Torino

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of ovine COX1 assessed as reduction in PGF2alpha production by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
University of Torino

Curated by ChEMBL
LigandPNGBDBM17636(2-{[3-(trifluoromethyl)phenyl]amino}benzoic acid |...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50278014(CHEMBL4163031)copy SMILEScopy InChI
Affinity DataIC50: 3.28E+4nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277996(CHEMBL4177097)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Compound was tested for binding affinity against retinoid X receptor using 5 nM of [3H]-9-cis-RA as a radioligand in baculovirus expressed receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50278015(CHEMBL4170286)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277999(CHEMBL4173733)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human AKR1C3 expressed in Escherichia coli BL21 (DE) using [14C]androstenedione as substrate in presence of NADPH generatin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50278013(CHEMBL4166887)copy SMILEScopy InChI
Affinity DataIC50: 6.29E+4nMAssay Description:Thromboxane (TXA2) receptor antagonist activity using human plateletMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
LigandPNGBDBM50585954(CHEMBL5092526)copy SMILES
Affinity DataIC50: 6.41E+4nMAssay Description:Inhibition of N-terminal-His6 tagged recombinant human ALDH3A1 assessed as reduction in NADPH production using 4-NBA and NADP+ as substrate by fluori...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19FTPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277997(CHEMBL4159654)copy SMILEScopy InChI
Affinity DataIC50: 7.06E+4nMAssay Description:Inhibition of AKR1C2 (unknown origin) using S-tetralol as substrate by by fluorimteryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetAldo-keto reductase family 1 member C2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)copy SMILEScopy InChI
Affinity DataIC50: 7.32E+4nMAssay Description:Inhibition of AKR1C2 (unknown origin) using S-tetralol as substrate by by fluorimteryMore data for this Ligand-Target Pair
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277998(CHEMBL4174786)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
TargetCytochrome c oxidase subunit 2(Homo sapiens (Human))
University of Torino

Curated by ChEMBL
LigandPNGBDBM50277997(CHEMBL4159654)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonistic activity against TP-receptor by inhibition of U 46619-induced contraction of isolated guinea pig tracheaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q52S4XPubMed
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