Compile Data Set for Download or QSAR
Found 666 with Last Name = 'schimpl' and Initial = 'm'
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM413448(9-((1r,4r)-4-hydroxycyclohexyl)-7-methyl-2-((7-met...)copy SMILEScopy InChI
Affinity DataIC50: 0.0794nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599239(CHEMBL5184141 | US11884671, Example 32)copy SMILES
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599238(CHEMBL5181303 | US11884671, Example 29)copy SMILES
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599237(CHEMBL5180090 | US11884671, Example 30)copy SMILES
Affinity DataIC50: 0.120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599240(CHEMBL5194436 | US11884671, Example 31)copy SMILES
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM413460(9-cyclohexyl-7-methyl-2-((7-methyl-[1,2,4]triazolo...)copy SMILEScopy InChI
Affinity DataIC50: 0.158nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526936(CHEMBL4450232)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526938(CHEMBL4553941)copy SMILEScopy InChI
Affinity DataIC50: 0.251nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM413456(9-((1r,4r)-4-hydroxy-4-methylcyclohexyl)-7-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526928(CHEMBL4555040)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599247(CHEMBL5197250)copy SMILES
Affinity DataIC50: 0.370nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526932(CHEMBL4474647)copy SMILEScopy InChI
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM413457(9-((1s,4s)-4-hydroxy-4-methylcyclohexyl)-7-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 0.398nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599234(CHEMBL5170489 | US11884671, Example 52)copy SMILES
Affinity DataIC50: 0.510nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM413450(7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM413450(7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM413450(7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 0.631nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599248(CHEMBL5179972)copy SMILES
Affinity DataIC50: 0.640nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599243(CHEMBL5192430 | US11884671, Example 37)copy SMILES
Affinity DataIC50: 0.690nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599242(CHEMBL5196848 | US11884671, Example 45)copy SMILES
Affinity DataIC50: 0.690nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM413450(7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridi...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of AlexaFluor-labeled tracer 236 binding to human untagged DNA-PK expressed in baculovirus expression system measured after 60 mins by Lan...More data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
PDB
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599245(CHEMBL5191577)copy SMILES
Affinity DataIC50: 0.75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50563635(CHEMBL4777640)copy SMILES
Affinity DataIC50: 0.794nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP78NCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599251(CHEMBL5198414 | US11884671, Example 42)copy SMILES
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50573136(CHEMBL4875486)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50172077(CHEMBL3810063)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599250(CHEMBL5178837)copy SMILES
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599246(CHEMBL5204870)copy SMILES
Affinity DataIC50: 1.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526941(CHEMBL4459057)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50573135(CHEMBL4873217)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526933(CHEMBL4438672)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50573128(CHEMBL4865752)copy SMILES
Affinity DataIC50: 2.5nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S18686PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599244(CHEMBL5182028 | US11884671, Example 41)copy SMILES
Affinity DataIC50: 2.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599249(CHEMBL5182752)copy SMILES
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50599236(CHEMBL5186637 | US11884671, Example 44)copy SMILES
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP57BCPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM553937(US11325906, Example 1)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D7JPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM553940(US11325906, Example 4)copy SMILES
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D7JPubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50172077(CHEMBL3810063)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP78NCPubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))TBA
LigandPNGBDBM50563640(CHEMBL4746916)copy SMILES
Affinity DataIC50: 3.20nMAssay Description:Inhibition of His6/TEV fused-GST-tagged Flt3 (unknown origin) (H564 to S993 residues) using Axltide (CKKSRGDYMTMQJ-acid) peptide as substrate preincu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP78NCPubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50573130(CHEMBL4855381)copy SMILES
Affinity DataIC50: 3.20nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S18686PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526931(CHEMBL4474502)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetTyrosine-protein kinase receptor UFO(Homo sapiens (Human))TBA
LigandPNGBDBM50563644(CHEMBL4782810)copy SMILES
Affinity DataIC50: 4nMAssay Description:Inhibition of GST-tagged AXL (unknown origin) (464 to 485 residues) using Axltide (CKKSRGDYMTMQJG-acid) peptide as substrate preincubated for 30 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP78NCPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50601780(CHEMBL5202060)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D7JPubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50601781(CHEMBL5197101)copy SMILES
Ligand InfoPC cidPC sidPDB
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))TBA
LigandPNGBDBM553947(US11325906, Example 11)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03D7JPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526937(CHEMBL4483014)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50563643(CHEMBL4754609)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of MER (unknown origin) by LC-MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
AstraZeneca

Curated by ChEMBL
LigandPNGBDBM50526935(CHEMBL4529390)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of human HeLa cell-derived full length DNA-PK catalytic subunit using fluorescein-EPPLSQEAFADLWKK as substrate preincubated for 30 mins fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z18Z4PubMed
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50563642(CHEMBL4746146)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTyrosine-protein kinase Mer(Homo sapiens (Human))TBA
LigandPNGBDBM50563643(CHEMBL4754609)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of 6His/thrombin cleavage site-fused Avi-tagged dephosphorylated MER (unknown origin) (R528 to M999 residues) using Axltide (CKKSRGDYMTMQJ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
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