Compile Data Set for Download or QSAR
Found 658 with Last Name = 'shiozaki' and Initial = 'm'
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557765(CHEMBL4791414)copy SMILES
Affinity DataIC50: 0.310nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557761(CHEMBL4758580)copy SMILES
Affinity DataIC50: 0.560nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557764(CHEMBL4787891)copy SMILES
Affinity DataIC50: 0.610nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557766(CHEMBL4751832)copy SMILES
Affinity DataIC50: 0.830nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557760(CHEMBL4749011)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557742(CHEMBL4752199)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM109863(US8609647, 1 | US8609647, 15 | US8609647, 2 | US86...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK2 kinase domain (aa808-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557753(CHEMBL4748097)copy SMILES
Affinity DataIC50: 1nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557756(CHEMBL4779273)copy SMILES
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167609((2R,5R)-1-[4-(2,4-Dichloro-benzyloxy)-benzenesulfo...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human JAK3 (780 to end residues) expressed in baculovirus infected Sf9 cells using TK-substrate-biotin as substrate incubated for 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7F2WPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal GST-fused human JAK2 (880 to end residues) expressed in baculovirus infected Sf21 cells using TK-substrate-biotin as substra...More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341824((1S,2R,3R)-2-Methyl-1-[5-(4-methylpyrazol-1-yl)thi...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557755(CHEMBL4782729)copy SMILES
Affinity DataIC50: 1.20nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341816((1S,2R,3R)-1-[5-(4-Methoxypyrazol-1-yl)thiophene-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50167609((2R,5R)-1-[4-(2,4-Dichloro-benzyloxy)-benzenesulfo...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557744(CHEMBL4741185)copy SMILES
Affinity DataIC50: 1.5nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557763(CHEMBL4744618)copy SMILES
Affinity DataIC50: 1.60nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM109863(US8609647, 1 | US8609647, 15 | US8609647, 2 | US86...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK2 kinase domain (aa808-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM109866(US8609647, 26 | US8609647, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK2 kinase domain (aa808-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM109867(US8609647, 27 | US8609647, 37 | US8609647, 5)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK2 kinase domain (aa808-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557767(CHEMBL4764221)copy SMILES
Affinity DataIC50: 2nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM109868(US8609647, 19 | US8609647, 21 | US8609647, 6)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK2 kinase domain (aa808-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM109865(US8609647, 25 | US8609647, 3 | US8609647, 59)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK2 kinase domain (aa808-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Inhibition of N-terminal GST-fused human JAK2 (880 to end residues) expressed in baculovirus infected Sf21 cells using TK-substrate-biotin as substra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7F2WPubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM50545650(Delgocitinib | JTE-052 | JTE-052A | LEO 124249 | L...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Inhibition of N-terminal GST-fused human JAK1 (850 to 1154 residues) expressed in baculovirus expression system using TK-substrate-biotin as substrat...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7F2WPubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50341819((1S,2R,3R)-1-(6-Chloro-4H-thieno[3,2-b]indole-2-su...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human recombinant aggrecanase 2 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557746(CHEMBL4779579)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of N-terminal GST-fused human JAK1 (850 to 1154 residues) expressed in baculovirus expression system using TK-substrate-biotin as substrat...More data for this Ligand-Target Pair
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557759(CHEMBL4763627)copy SMILES
Affinity DataIC50: 2.90nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557745(CHEMBL4741913)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557757(CHEMBL4792464)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50104963((2S,3R)-2-(cyclopropylmethylamino)-N1-hydroxy-N4-(...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM109867(US8609647, 27 | US8609647, 37 | US8609647, 5)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557754(CHEMBL4764416)copy SMILES
Affinity DataIC50: 3.30nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM109863(US8609647, 1 | US8609647, 15 | US8609647, 2 | US86...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant MMP14 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetCollagenase 3(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human recombinant MMP13 after 60 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557758(CHEMBL4749061)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557743(CHEMBL4744988)copy SMILES
Affinity DataIC50: 3.70nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557747(CHEMBL4795223)copy SMILES
Affinity DataIC50: 3.90nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Central Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50311088(CHEMBL1078281 | cis-rac-1-(5-(4-chloro-1H-pyrazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant aggrecanase 1 after 150 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87B3DPubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM109867(US8609647, 27 | US8609647, 37 | US8609647, 5)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM109863(US8609647, 1 | US8609647, 15 | US8609647, 2 | US86...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Japan Tobacco Inc.

US Patent
LigandPNGBDBM109869(US8609647, 7 | US8609647, 84)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK2 kinase domain (aa808-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTGF-beta receptor type-2(Homo sapiens (Human))TBA
LigandPNGBDBM50557739(CHEMBL4798505)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of TGFbeta receptor 2 (unknown origin) using biotin-labelled TTLKDLIYDMTTSGSGSGLPLLVQRTIARTsubstrate in presence of [gamma33P] ATP measure...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1WD5PubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM109866(US8609647, 26 | US8609647, 4)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM109869(US8609647, 7 | US8609647, 84)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM109909(US8609647, 54 | US8609647, 66)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:In the kinase reactions, fused proteins (6His tag-fused hJAK3 kinase domain (aa781-end)) which were coexpressed in Sf21 cells and purified by Ni2+/NT...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C6W24US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Japan Tobacco Inc.

Curated by ChEMBL
LigandPNGBDBM109867(US8609647, 27 | US8609647, 37 | US8609647, 5)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human JAK3 (780 to end residues) expressed in baculovirus infected Sf9 cells using TK-substrate-biotin as substrate incubated for 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX7F2WPubMed
Displayed 1 to 50 (of 658 total ) | Next | Last >>
Jump to: