Compile Data Set for Download or QSAR
Found 229 with Last Name = 'subramanian' and Initial = 'm'
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM198665(US9221796, 2b)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM198694(US9221796, 23b)copy SMILEScopy InChI
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM198728(US9221796, 46, P-4)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM198726(US9221796, 46, P-2)copy SMILEScopy InChI
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50330324(CHEMBL4170867)copy SMILEScopy InChI
Affinity DataKi:  4.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM198728(US9221796, 46, P-4)copy SMILEScopy InChI
Affinity DataKi:  6.30nMAssay Description:Binding affinity to GluN2B receptor in human cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50330409(CHEMBL4168402)copy SMILEScopy InChI
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50330410(CHEMBL4161899)copy SMILEScopy InChI
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM198735(US9221796, 48, P-3)copy SMILEScopy InChI
Affinity DataKi:  11nMAssay Description:Displacement of [3H]Ro 25-6981 from GluN2B receptor in Sprague-Dawley rat forebrain membranes incubated for 1 hr by topcount micro scintillation coun...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetToll-like receptor 7(Mus musculus)TBA
LigandPNGBDBM21958(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM13934(Atazanavir | BMS 232632 | CGP 73547 | CHEMBL1163 |...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM21958(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM443496(US10660877, Example 73)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM443500(US10660877, Example 77)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM442004(US10660877, Example 31)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM21958(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperi...)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM21958(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM441973(2-(2-fluoro-6-methylpyridin-4-yl)-3-isopropyl-5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM443111(US10660877, Example 46)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM442004(US10660877, Example 31)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM443496(US10660877, Example 73)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM443506(US10660877, Example 83)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM443500(US10660877, Example 77)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM21958(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM441973(2-(2-fluoro-6-methylpyridin-4-yl)-3-isopropyl-5-(p...)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM441974(US10660877, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523563(CHEMBL4554438)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523569(CHEMBL4463796)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523559(CHEMBL4573907)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523568(CHEMBL4447493)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523567(CHEMBL4522729)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523564(CHEMBL4525849)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523565(CHEMBL4542773)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523566(CHEMBL4574382)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523558(CHEMBL4460401)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523560(CHEMBL4300203)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523561(CHEMBL4437104)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
TBA

Curated by ChEMBL
LigandPNGBDBM50523562(CHEMBL4474072)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of HIV1 protease activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP066SPubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM198665(US9221796, 2b)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Binding affinity to GluN2B receptor in human cortexMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PR7ZJTPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM21958(2-(2,6-dimethylpyridin-4-yl)-3-isopropyl-5-(piperi...)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMMore data for this Ligand-Target Pair
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50543465(CHEMBL4636498)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Antagonist activity at TLR7 (unknown origin) in PBMC cells assessed as reduction of IL-6 productionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N55THPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM50543465(CHEMBL4636498)copy SMILEScopy InChI
Affinity DataIC50: 5.10nMAssay Description:Antagonist activity at TLR8 in human whole blood cells assessed as inhibition of IL-6 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N55THPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50543465(CHEMBL4636498)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at TLR7 in human whole blood cells assessed as inhibition of gardiquimod induced IL-6 production by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N55THPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM441974(US10660877, Example 5)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM442800(US10660877, Example 38)copy SMILEScopy InChI
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM442804(US10660877, Example 39)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM441989(US10660877, Example 19)copy SMILEScopy InChI
Affinity DataIC50: 7.60nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM443498(US10660877, Example 75)copy SMILEScopy InChI
Affinity DataIC50: 8.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 8(Homo sapiens (Human))TBA
LigandPNGBDBM443111(US10660877, Example 46)copy SMILEScopy InChI
Affinity DataIC50: 9.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3R6PPubMed
TargetToll-like receptor 7(Homo sapiens (Human))TBA
LigandPNGBDBM50543465(CHEMBL4636498)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Antagonist activity at human TLR7 overexpressed in HEK-Blue cells assessed as inhibition of gardiquimod-induced NFkappaB and AP-1 activation preincub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22N55THPubMed
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