TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Displacement of 9-cis-[11,12-3H]-retinoic acid from human RXRalpha LBD incubated for overnight by scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 150nMAssay Description:Displacement of 9-cis-[11,12-3H]-retinoic acid from human RXRalpha LBD incubated for overnight by scintillation counting methodMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 182nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 182nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 201nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21(DE3) incubated for 1 hr in presence of compound by [3...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2GT5RVFPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2GT5RVFPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of 9-cis-[11,12-3H]-retinoic acid from human RXRalpha LBD incubated for overnight by scintillation counting methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 230nMAssay Description:Displacement of 9-cis-[11,12-3H]-retinoic acid from human RXRalpha LBD incubated for overnight by scintillation counting methodMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 350nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21(DE3) incubated for 1 hr in presence of compound by fl...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2GT5RVFPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2GT5RVFPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 379nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 379nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 583nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 583nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 6.29E+3nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 6.29E+3nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 7.63E+3nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKi: 7.63E+3nMAssay Description:Displacement of CU-6PMN from human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataIC50: 632nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21(DE3) incubated for 1 hr in presence of compound by fl...More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2GT5RVFPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2GT5RVFPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human RXRalpha LBD expressed in African green monkey COS1 cells incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 375nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21(DE3) incubated for 1 hr by fluorescence polarization ...More data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 761nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21(DE3) incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 629nMAssay Description:Binding affinity to human RXRalpha-LBD (224 to 462 residues) expressed in Escherichia coli BL21(DE3) incubated for 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human RXRalpha LBD expressed in African green monkey COS1 cells incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human RXRalpha LBD expressed in African green monkey COS1 cells incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 233nMAssay Description:Binding affinity to human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human RXRalpha LBD expressed in African green monkey COS1 cells incubated for 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2G44TRNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Okayama University Graduate School of Medicine
Curated by ChEMBL
Okayama University Graduate School of Medicine
Curated by ChEMBL
Affinity DataKd: 233nMAssay Description:Binding affinity to human RXRalpha LBD incubated for 2 hrs by fluorescence based assayMore data for this Ligand-Target Pair