Compile Data Set for Download or QSAR
Found 646 with Last Name = 'vicchiarelli' and Initial = 'm'
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)copy SMILEScopy InChI
Affinity DataKi:  340nMAssay Description:Inhibition of TNAP using CDP-star as substrate by non-competitive Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)copy SMILEScopy InChI
Affinity DataKi:  410nMAssay Description:Binding affinity to sigma-1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JZQPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)copy SMILEScopy InChI
Affinity DataKi:  590nMAssay Description:Inhibition of TNAP using DEA as substrate by non-competitive Lineweaver-Burk plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to 5-HT3 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JZQPubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)copy SMILEScopy InChI
Affinity DataKi:  1.42E+3nMAssay Description:Binding affinity to histamine H1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JZQPubMed
TargetTranslocator protein(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440737(CHEMBL2431120)copy SMILEScopy InChI
Affinity DataKi:  2.54E+3nMAssay Description:Binding affinity to PBR receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JZQPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50248035((2S)-2-(1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxy...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of NTS1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9KQ0PubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50248035((2S)-2-(1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxy...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of MOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9KQ0PubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50248035((2S)-2-(1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxy...)copy SMILEScopy InChI
Affinity DataKi:  5.20E+3nMAssay Description:Inhibition of DOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9KQ0PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)copy SMILEScopy InChI
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of NTS1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9KQ0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50248035((2S)-2-(1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxy...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9KQ0PubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50444943(CHEMBL3099773)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9KQ0PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125I]-neurotensin from NTR1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NV9KQ0PubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Displacement of [125I]-neurotensin from NTR1 in HUVEC after 1 hr by gamma counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JZQPubMed
LigandPNGBDBM62288(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetNeurotensin receptor type 1(Homo sapiens (Human))
Conrad Prebys Center for Chemical Genomics at Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50440738(CHEMBL2431105)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Antagonist activity at NTR1 (unknown origin) expressed in human U2OS cells coexpressing beta-arrestin assessed as inhibition of ML314-induced effect ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JZQPubMed
LigandPNGBDBM62288(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-[4-(tr...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM62170(1-(4-chlorophenyl)sulfonyl-2-benzimidazolamine | 1...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299534(5-Bromo-2-methoxy-N-(quinolin-3-yl)benzenesulfonam...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM54409(4-[4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of TNAP right after mixing with enzyme (EI 0:0) by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM62261(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of TNAP after 1 hr incubation with enzyme post-dilution (EI 1:0) by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM62251(MLS-0412140.0001 | cid_44182145 | cyclopropyl-[2-m...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM62261(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299523(2,5-Dimethoxy-N-(quinolin-3-yl)benzenesulfonamide ...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of TNAP after 1 hr pre-incubation with enzyme (EI 1:1) by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM62257(MLS-0360553.0001 | cid_20901691 | cyclopropyl-[5-[...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM54409(4-[4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM62295(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299525(5-chloro-2-methoxy-4-methyl-N-(pyridin-3-yl)benzen...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM62257(MLS-0360553.0001 | cid_20901691 | cyclopropyl-[5-[...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299526(5-chloro-2-ethoxy-N-(pyridin-3-yl)benzenesulfonami...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM59542((1-tosylbenzimidazol-2-yl)amine | 1-(4-methylpheny...)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM59544(4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-eth...)copy SMILEScopy InChI
Affinity DataIC50: 570nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM62249(1-[5-[4-(4-chlorophenyl)piperazin-1-yl]sulfonyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299535(2-Methoxy-5-methyl-N-(quinolin-3-yl)benzenesulfona...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299527(5-chloro-2-ethoxy-4-methyl-N-(pyridin-3-yl)benzene...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
TargetApelin receptor(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM50393964(CHEMBL2158347)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:Antagonist activity at APJ receptor assessed as inhibition of apelin13-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H1333BPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299536(2-Methoxy-4-nitro-N-(quinolin-3-yl)benzenesulfonam...)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM62295(4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:Inhibition of NOD-2 mediated NFkappaB activation in HEK293T cells assessed as inhibition of MDP-induced luciferase activity after 14 hrs by reporter ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM54413(CHEMBL1612423 | MLS001202690 | N-(4-Chloro-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetGlucose-6-phosphate dehydrogenase(Plasmodium falciparum)
University of California

Curated by ChEMBL
LigandPNGBDBM50396489(CHEMBL2170943)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MM3PubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44446(4-[2-[[(5Z)-5-(3-indolylidene)-4-(2-methoxyethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WKPPubMed
TargetMannose-6-phosphate isomerase(Homo sapiens (Human))
Sanford-Burnham Medical Research Institute

Curated by ChEMBL
LigandPNGBDBM44461(5-[(2-methoxyphenyl)-oxomethoxy]-1-phenyl-3-pyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human purified phosphomannose isomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WKPPubMed
LigandPNGBDBM62249(1-[5-[4-(4-chlorophenyl)piperazin-1-yl]sulfonyl-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
LigandPNGBDBM62302(MLS-0425608.0001 | N-(4-bromophenyl)-4-(3,4-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
TargetAlkaline phosphatase, tissue-nonspecific isozyme(Homo sapiens (Human))
Institute for Medical Research

Curated by ChEMBL
LigandPNGBDBM50299524(2,5-Dimethoxy-N-(pyridin-3-yl)benzenesulfonamide |...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of TNAP transfected in african green monkey COS1 cells by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T9MPubMed
LigandPNGBDBM59544(4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-eth...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of NOD-1 mediated NFkappaB activation in HEK293T cells assessed as inhibition of gamma-tri-DAP-induced luciferase activity after 14 hrs by...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9966ZPubMed
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