Compile Data Set for Download or QSAR
Found 158 with Last Name = 'zoeckler' and Initial = 'm'
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Concentration required to inhibit Cytochrome P450 1A2 in vitro by 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Concentration required to inhibit Cytochrome P450 2C9 in vitro by 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Concentration required to inhibit cytochrome P450 isozyme CYP3A4-BzRes in vitro by 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Concentration required to inhibit cytochrome P450 isozyme CYP3A4-BFC in vitro by 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Concentration required to inhibit cytochrome P450 isozyme CYP2C19 in vitro by 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209387(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(6-(4...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50209380((S)-3-(6-bromo-4-methyl-1H-benzo[d]imidazol-2-yl)-...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of CYP1A2 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209385(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50206136(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209389(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 68nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin receptor(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:In vitro inhibitory concentration against IR kinase with ATP concentration at 1/2KmMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50206120(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209392(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory concentration against IGF-1R kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory concentration against IGF-1R Sal kinase with ATP concentration at 1/2KmMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209391(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201135(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201144(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201132(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:In vitro inhibitory concentration against FAK with ATP concentration at 1/2KmMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201138(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209382(2-(4-{[2-(3-chlorophenyl)-2-hydroxyethyl]amino}-2-...)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209386(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory concentration against IGF-1R kinaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209394(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:In vitro inhibitory concentration against MEK with ATP concentration at 1/2KmMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201133(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201135(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of IGF1R expressed in Sal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201126(3-(2-(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201129(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209393(2-(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201128(CHEMBL388206 | N-(3-(2-(3-(6-(1H-imidazol-1-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201143(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)copy SMILEScopy InChI
Affinity DataIC50: 341nMAssay Description:In vitro inhibitory concentration against LCK with ATP concentration at 1/2KmMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201123(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50209391(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Inhibition of CYP3A4 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201124(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Inhibition of IGF1R expressed in Sal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM50209378(4-(2-(3-chlorophenyl)-2-hydroxyethylamino)-3-(4-me...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Inhibition of CYP1A2 in microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206120(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 390nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201143(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of IGF1R expressed in Sal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201130(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 440nMAssay Description:Inhibition of IGF1R expressed in Sal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201120(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201134(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of IGF1R expressed in Sal cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol-Myers Squibb Co

Curated by ChEMBL
LigandPNGBDBM27879(4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Concentration required to inhibit cytochrome P450 isozyme CYP3A4-BFC in vitro by 50%More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2GPPPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201137(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201134(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 520nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50206136(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76C71PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50201125(3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidaz...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3K4DPubMed
Displayed 1 to 50 (of 158 total ) | Next | Last >>
Jump to: