Compile Data Set for Download or QSAR
Found 43 with Last Name = 'zolli-juran' and Initial = 'm'
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130955(3-amino-1-{[4-({[[(aminocarbonothioyl)amino](imini...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)copy SMILEScopy InChI
Affinity DataKi:  38nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130956(5-(4-methylphenoxy)quinazoline-2,4-diamine, 2a | 5...)copy SMILEScopy InChI
Affinity DataKi:  41nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)copy SMILEScopy InChI
Affinity DataKi:  61nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130951(CHEMBL85364 | N-(4-chloro-2-cyanophenyl)imidodicar...)copy SMILEScopy InChI
Affinity DataKi:  65nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)copy SMILEScopy InChI
Affinity DataKi:  73nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130952(5-(4-(trifluoromethyl)benzyloxy)quinazoline-2,4-di...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)copy SMILEScopy InChI
Affinity DataKi:  150nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N6GPubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

LigandPNGBDBM59168(5-(4-fluorophenoxy)quinazoline-2,4-diamine, 2b)copy SMILEScopy InChI
Affinity DataKi:  180nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N6GPubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130954(6,7-Dimethyl-4a,5,6,7,8,8a-hexahydro-quinazoline-2...)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

LigandPNGBDBM50130956(5-(4-methylphenoxy)quinazoline-2,4-diamine, 2a | 5...)copy SMILEScopy InChI
Affinity DataKi:  230nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N6GPubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

LigandPNGBDBM59166(6,7-dimethyl-5,6,7,8-tetrahydroquinazoline-2,4-dia...)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639N6GPubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

LigandPNGBDBM59167(6-methyl-5,6,7,8-tetrahydroquinazoline-2,4-diamine...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition assay using Esherichia coli dihydrofolate reductase (DHFR). More data for this Ligand-Target Pair
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130953(2,4-Diamino-1,6-bis-(4-fluoro-phenyl)-[1,3,5]triaz...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130957(3-Heptyl-4-hydroxy-1H-quinolin-2-one | CHEMBL80014)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130958(7-Methyl-4a,5,6,7,8,8a-hexahydro-quinazoline-2,4-d...)copy SMILEScopy InChI
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM18069(5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 37nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130955(3-amino-1-{[4-({[[(aminocarbonothioyl)amino](imini...)copy SMILEScopy InChI
Affinity DataIC50: 109nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130955(3-amino-1-{[4-({[[(aminocarbonothioyl)amino](imini...)copy SMILEScopy InChI
Affinity DataIC50: 302nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130951(CHEMBL85364 | N-(4-chloro-2-cyanophenyl)imidodicar...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130956(5-(4-methylphenoxy)quinazoline-2,4-diamine, 2a | 5...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130956(5-(4-methylphenoxy)quinazoline-2,4-diamine, 2a | 5...)copy SMILEScopy InChI
Affinity DataIC50: 420nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130950(5-(4-Chloro-phenylsulfanyl)-quinazoline-2,4-diamin...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130951(CHEMBL85364 | N-(4-chloro-2-cyanophenyl)imidodicar...)copy SMILEScopy InChI
Affinity DataIC50: 620nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130952(5-(4-(trifluoromethyl)benzyloxy)quinazoline-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130954(6,7-Dimethyl-4a,5,6,7,8,8a-hexahydro-quinazoline-2...)copy SMILEScopy InChI
Affinity DataIC50: 790nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM18046(5-((4-methylphenyl)thio)-quinazoline 2,4-diamine, ...)copy SMILEScopy InChI
Affinity DataIC50: 820nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130952(5-(4-(trifluoromethyl)benzyloxy)quinazoline-2,4-di...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130954(6,7-Dimethyl-4a,5,6,7,8,8a-hexahydro-quinazoline-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130958(7-Methyl-4a,5,6,7,8,8a-hexahydro-quinazoline-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130953(2,4-Diamino-1,6-bis-(4-fluoro-phenyl)-[1,3,5]triaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130953(2,4-Diamino-1,6-bis-(4-fluoro-phenyl)-[1,3,5]triaz...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition constant against Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130958(7-Methyl-4a,5,6,7,8,8a-hexahydro-quinazoline-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 100 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130957(3-Heptyl-4-hydroxy-1H-quinolin-2-one | CHEMBL80014)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of Escherichia coli Dihydrofolate reductase in presence of 30 uM Dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed
TargetDihydrofolate reductase(Escherichia coli)
McMaster University

Curated by ChEMBL
LigandPNGBDBM50130957(3-Heptyl-4-hydroxy-1H-quinolin-2-one | CHEMBL80014)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition constant of compound against dihydrofolate reductaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CN74G5PubMed