TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Agonist activity at human glucocorticoid receptor in PBMC assessed as inhibition of LPS-induced TNFalpha releaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Inhibition of N-terminal His-tagged human JAK3 catalytic domain incubated for 20 mins in presence of TK substrate-biotin by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Agonist activity at human glucocorticoid receptor in PBMC assessed as inhibition of LPS-induced TNFalpha releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Agonist activity at human glucocorticoid receptor in PBMC assessed as inhibition of LPS-induced TNFalpha releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Agonist activity at human glucocorticoid receptor in PBMC assessed as inhibition of LPS-induced TNFalpha releaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 2.70nMAssay Description:Inhibition of N-terminal His-tagged human JAK2 catalytic domain incubated for 20 mins in presence of TK substrate-biotin by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 3.40nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 6.90nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Agonist activity at human glucocorticoid receptor in PBMC assessed as inhibition of LPS-induced TNFalpha releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Agonist activity at human glucocorticoid receptor in PBMC assessed as inhibition of LPS-induced TNFalpha releaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Agonist activity at human glucocorticoid receptor in PBMC assessed as inhibition of LPS-induced TNFalpha releaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Agonist activity at human glucocorticoid receptor in PBMC assessed as inhibition of LPS-induced TNFalpha releaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 9.30nMAssay Description:Inhibition of human Gst-tagged JAK1 (850 to 1154 residues) expressed in baculovirus using biotin-synthetic peptide as substrate after 40 mins by HTRF...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged JAK3 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of human His-tagged JAK2 expressed in baculovirus using biotin-synthetic peptide as substrate after 20 mins by HTRF assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
GVK Biosciences Private Limited
Curated by ChEMBL
GVK Biosciences Private Limited
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of N-terminal GST-tagged human JAK1 catalytic domain (850 to 1154 residues) incubated for 40 mins in presence of TK substrate-biotin by TR...More data for this Ligand-Target Pair