Compile Data Set for Download or QSAR
Found 123 with Last Name = 'glicksman' and Initial = 'ma'
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)copy SMILEScopy InChI
Affinity DataIC50: 0.0160nMAssay Description:Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase of chicken gizzardMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM6760((+)-K-252a | CHEMBL281948 | K-252a | methyl (15S,1...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetcAMP-dependent protein kinase(Oryctolagus cuniculus (Rabbit))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058332(CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of cAMP dependent Protein kinase A of rabbit Skeletal Muscle.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058332(CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of Smooth muscle myosin light chain kinase of chicken gizzardMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of DYRK1AMore data for this Ligand-Target Pair
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311312(CHEMBL1078739 | N-(2-chlorophenyl)-6-phenylimidazo...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311306(CHEMBL1078214 | N-(2-chlorophenyl)-5-(piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311302(CHEMBL1078107 | N-(2-chlorophenyl)-5-phenylpyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311303(CHEMBL1077571 | N-(2-chlorophenyl)-5-(dimethylamin...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311316(CHEMBL1077739 | LDN-211904 | N-(2-chlorophenyl)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311313(CHEMBL1078840 | N-(2-chlorophenyl)-6-(piperidin-1-...)copy SMILEScopy InChI
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379521(CHEMBL2012574)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379526(CHEMBL2012563)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527](Homo sapiens (Human))
Harvard NeuroDiscovery Center

LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:The kinase assays for phosphorylation of LRRKtide (RLGRDKYKTLRQIRQ) or LRRKtideS (RLGRDKYKSLRQIRQ) were conducted in buffer containing 20 mM HEPES (p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4NT5PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379512(CHEMBL2012559)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311318(6-bromo-N-(2-chlorophenyl)-2-methylimidazo[1,2-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311301(CHEMBL1080959 | N-(2-chlorophenyl)-5-methoxypyrazo...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379525(CHEMBL2012562)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311304(CHEMBL1078108 | N-(2-chlorophenyl)-5-(1H-pyrrol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527](Homo sapiens (Human))
Harvard NeuroDiscovery Center

LigandPNGBDBM228657(GSK3-XIII)copy SMILEScopy InChI
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:The kinase assays for phosphorylation of LRRKtide (RLGRDKYKTLRQIRQ) or LRRKtideS (RLGRDKYKSLRQIRQ) were conducted in buffer containing 20 mM HEPES (p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4NT5PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058336(CHEMBL53885 | methyl 10,23-di(ethoxymethyl)-16-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379522(CHEMBL2012575)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379516(CHEMBL2012569)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311317(CHEMBL1077740 | N-(2-chlorophenyl)-6-(4-hydroxypip...)copy SMILEScopy InChI
Affinity DataIC50: 228nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311305(CHEMBL1078109 | N-(2-chlorophenyl)-5-morpholinopyr...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311296(CHEMBL1081498 | N-(2-chlorophenyl)-5-methylpyrazol...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058333(CHEMBL291985 | methyl 16-hydroxy-10,23-di(methoxym...)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379511(CHEMBL2012560)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379519(CHEMBL2012572)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379524(CHEMBL2012561)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311311(CHEMBL1078738 | N-(2-chlorophenyl)imidazo[1,2-a]py...)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379523(CHEMBL2012558)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379520(CHEMBL2012573)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379517(CHEMBL2012570)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379527(CHEMBL2012564)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379528(CHEMBL2012565)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataIC50: 690nMAssay Description:Inhibition of DYRK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50778((1S,2S,3R,8aS)-6-acetyl-3-carbamoyl-1-cyano-2-(3-t...)copy SMILEScopy InChI
Affinity DataIC50: 770nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527,I2020T](Homo sapiens (Human))
Harvard NeuroDiscovery Center

LigandPNGBDBM50322535(3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N...)copy SMILEScopy InChI
Affinity DataIC50: 800nMpH: 7.4 T: 2°CAssay Description:The kinase assays for phosphorylation of LRRKtide (RLGRDKYKTLRQIRQ) or LRRKtideS (RLGRDKYKSLRQIRQ) were conducted in buffer containing 20 mM HEPES (p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4NT5PubMed
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50379518(CHEMBL2012571)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of human recombinant N-terminal MBP-tagged haspin kinase expressed in Escherichia coli DE3 after 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058335(CHEMBL433281 | methyl 10,23-di(allylsulfanylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetEphrin type-B receptor 3(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50311288(CHEMBL1078785 | N-(2-chlorophenyl)pyrazolo[1,5-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43T66PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058334(CHEMBL301144 | methyl 16-hydroxy-10,23-di(isopropy...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058329(CHEMBL55567 | methyl 16-hydroxy-15-methyl-3-oxo-10...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058331(CHEMBL444039 | methyl 10,23-di(butylsulfanylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50058332(CHEMBL299496 | methyl 10,23-di(ethylsulfanylmethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to inhibit human trk A tyrosine kinase expressed in baculovirus using ELISA based enzyme assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95891PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2 [970-2527,I2020T](Homo sapiens (Human))
Harvard NeuroDiscovery Center

LigandPNGBDBM228657(GSK3-XIII)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 7.4 T: 2°CAssay Description:The kinase assays for phosphorylation of LRRKtide (RLGRDKYKTLRQIRQ) or LRRKtideS (RLGRDKYKSLRQIRQ) were conducted in buffer containing 20 mM HEPES (p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4NT5PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50778((1S,2S,3R,8aS)-6-acetyl-3-carbamoyl-1-cyano-2-(3-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of DYRK2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29KKPubMed
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