Compile Data Set for Download or QSAR
Found 46 with Last Name = 'hena' and Initial = 'ma'
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382321(CHEMBL2024688)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382322(CHEMBL2024689)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382324(CHEMBL2024691)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382320(CHEMBL2024687)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382318(CHEMBL2024685)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382319(CHEMBL2024686)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382325(CHEMBL2024693)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382323(CHEMBL2024690)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25437((trifluoromethyl)benzonitrile, 14 | 4-{[(1R,2S)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50221436(4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382318(CHEMBL2024685)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382325(CHEMBL2024693)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382324(CHEMBL2024691)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50221436(4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzo...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetActivin receptor type-1B(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of ALK4More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM25437((trifluoromethyl)benzonitrile, 14 | 4-{[(1R,2S)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382321(CHEMBL2024688)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382326(CHEMBL2024692)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of ALK5More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382323(CHEMBL2024690)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382319(CHEMBL2024686)copy SMILEScopy InChI
Affinity DataIC50: 135nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)copy SMILEScopy InChI
Affinity DataIC50: 196nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6BWTPubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)copy SMILEScopy InChI
Affinity DataIC50: 211nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382322(CHEMBL2024689)copy SMILEScopy InChI
Affinity DataIC50: 274nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382320(CHEMBL2024687)copy SMILEScopy InChI
Affinity DataIC50: 695nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetTGF-beta receptor type-1(Mus musculus)
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382326(CHEMBL2024692)copy SMILEScopy InChI
Affinity DataIC50: 708nMAssay Description:Inhibition of ALK5 in mouse NIH/3T3 cells by smad binding element reporter based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetL-lactate dehydrogenase C chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234443(N-Ethyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50382317(CHEMBL2024684)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ALK1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QC04H9PubMed
TargetL-lactate dehydrogenase C chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234444(N-Propyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase C chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM23222(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase B chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234443(N-Ethyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+4nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase B chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM23222(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+4nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM23222(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234443(N-Ethyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+5nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase C chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234447(N-sec-Butyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase C chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234445(N-Butyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+5nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase B chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234444(N-Propyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 8.87E+5nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234444(N-Propyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase C chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234446(N-Isobutyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234446(N-Isobutyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase B chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234446(N-Isobutyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase B chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234445(N-Butyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234445(N-Butyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 9.10E+6nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase A chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234447(N-sec-Butyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+7nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed
TargetL-lactate dehydrogenase B chain(Mus musculus (Mouse))
Instituto Politécnico Nacional

LigandPNGBDBM234447(N-sec-Butyl oxamate)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+7nMpH: 7.4Assay Description:Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78D36PubMed