TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.600nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -50.9kJ/molepH: 7.5 T: 2°CAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.70nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 2.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 2.70nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 3.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 3.30nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 4.20nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Aerie Pharmaceuticals, Inc.
Curated by ChEMBL
Affinity DataKi: 4.80nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...More data for this Ligand-Target Pair