Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.10nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.40nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.80nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.90nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.20nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
Affinity DataKi: 3.60nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.80nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.10nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
Affinity DataKi: 4.20nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.70nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.40nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.60nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 6.90nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 8nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataKi: 8.40nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.5nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
Affinity DataKi: 9.30nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2T154M1PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2T154M1PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant CA2 by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2XK8FDNPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataKi: 12nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 12nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2J38TJRPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2J38TJRPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataKi: 13nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 13nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 14.1nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 14.1nMAssay Description:Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assayMore data for this Ligand-Target Pair
Affinity DataKi: 15nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human carbonic anhydrase 9More data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant CA9 catalytic domain by stopped-flow CO2 hydrase assayMore data for this Ligand-Target Pair
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant carbonic anhydrase 9 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Neurocrine Biosciences
Curated by ChEMBL
Neurocrine Biosciences
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Displacement of [3H]dofetolide from human ERG channel expressed in HEK293 cells at 37 degC by liquid scintillation assayMore data for this Ligand-Target Pair