Compile Data Set for Download or QSAR
Found 26 with Last Name = 'wax' and Initial = 'mb'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 1.27nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 3.08nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 5.27nMAssay Description:Inhibition of VEGF-stimulated VEGFR-2 autophosphorylation in intact cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 8.5nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 8.79nMAssay Description:Inhibition of recombinant FGFR-2 tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 10.1nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 10.6nMAssay Description:Inhibition of recombinant VEGFR-2 tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 11.1nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 33.9nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 54.2nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetTyrosine-protein kinase Fyn(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 161nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetAurora kinase B(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 207nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 419nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of recombinant PDGFR tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetAquaporin-1(Homo sapiens (Human))
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM50089038(CGP 71683 | CGP-71683A | CHEMBL17645 | N-{[(1r,4r)...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 3.12E+3nMAssay Description:In Vitro Inhibition of Tyrosine Kinases using a 10-point Titration Curve.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetAquaporin-1(Homo sapiens (Human))
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM50354083(CHEMBL1836102 | N-{[(1r,4r)-4-{[(4-aminoquinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetAquaporin-1(Homo sapiens (Human))
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM178091(5-chloro-N-{[(1r,4r)-4-{[(4-aminoquinazolin-2-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 5.85E+3nMAssay Description:Inhibition of recombinant EGFR tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetAquaporin-1(Homo sapiens (Human))
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM178092({[7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetInsulin receptor(Homo sapiens (Human))
PanOptica, Inc.

US Patent
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant IR tyrosine kinase using exogenous substrate.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetAquaporin-1(Homo sapiens (Human))
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM178093([7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-ben...)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+4nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetAquaporin-1(Homo sapiens (Human))
Novartis Institutes of Biomedical Research Institute

LigandPNGBDBM178094({[7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)copy SMILEScopy InChI
Affinity DataIC50: 2.94E+4nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed