Compile Data Set for Download or QSAR
Found 174 with Last Name = 'eldefrawi' and Initial = 'me'
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50001028((+)-PENTAZOCINE | (-)-pentazocine | (2R,6R,11R)-6,...)copy SMILEScopy InChI
Affinity DataKi:  3.80nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040191(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  125nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)copy SMILEScopy InChI
Affinity DataKi:  168nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040192(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-azepane | C...)copy SMILEScopy InChI
Affinity DataKi:  674nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040197(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  720nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040199(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-piperidine...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040195(1-Benzo[b]thiophen-2-yl-cyclopentylamine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataKi:  1.73E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM83449(1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...)copy SMILEScopy InChI
Affinity DataKi:  1.77E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040189(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-piperidine...)copy SMILEScopy InChI
Affinity DataKi:  2.23E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040196(1-(1-Benzo[b]thiophen-2-yl-cycloheptyl)-azepane | ...)copy SMILEScopy InChI
Affinity DataKi:  2.71E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040198(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane | ...)copy SMILEScopy InChI
Affinity DataKi:  2.89E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040190(1-Benzo[b]thiophen-2-yl-cyclohexylamine | CHEMBL18...)copy SMILEScopy InChI
Affinity DataKi:  3.17E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040194(1-Benzo[b]thiophen-2-yl-cycloheptylamine | CHEMBL1...)copy SMILEScopy InChI
Affinity DataKi:  9.17E+3nMAssay Description:Inhibition of [3H](+)-pentazocine binding to sigma receptor of guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50089157((3R,5S,7aR)-3-Heptyl-5-methyl-hexahydro-pyrrolizin...)copy SMILEScopy InChI
Affinity DataKi:  5.00E+4nMAssay Description:Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KCVPubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50089159((3R,5S)-3,5-Dibutyl-octahydro-indolizine | CHEMBL2...)copy SMILEScopy InChI
Affinity DataKi:  3.70E+5nMAssay Description:Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KCVPubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50089158((3R,5R)-3,5-Dibutyl-octahydro-indolizine | CHEMBL2...)copy SMILEScopy InChI
Affinity DataKi:  4.20E+5nMAssay Description:Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KCVPubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50089162(7-((3R,5S,7aR)-5-Propyl-hexahydro-pyrrolizin-3-yl)...)copy SMILEScopy InChI
Affinity DataKi:  8.30E+5nMAssay Description:Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KCVPubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50089163((R)-7-((3R,5S,7aR)-5-Propyl-hexahydro-pyrrolizin-3...)copy SMILEScopy InChI
Affinity DataKi:  3.10E+6nMAssay Description:Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KCVPubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50089164((S)-7-((3R,5S,7aR)-5-Propyl-hexahydro-pyrrolizin-3...)copy SMILEScopy InChI
Affinity DataKi:  3.10E+6nMAssay Description:Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KCVPubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50089160((S)-7-((3R,5S,7aR)-5-Methyl-hexahydro-pyrrolizin-3...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+6nMAssay Description:Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KCVPubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Toyama Medical and Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50089161((R)-7-((3R,5S,7aR)-5-Methyl-hexahydro-pyrrolizin-3...)copy SMILEScopy InChI
Affinity DataKi:  8.30E+6nMAssay Description:Compound was evaluated for inhibition of [3H]-TCP binding to Nicotinic acetylcholine receptor of Torpedo californicaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3KCVPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043303((1-Benzo[b]thiophen-2-yl-cyclohexyl)-butyl-amine |...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50005534(1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...)copy SMILEScopy InChI
Affinity DataIC50: 0.660nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043292((1-Benzo[b]thiophen-2-yl-cyclohexyl)-cyclopropylme...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50455447(CHEMBL2112946)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition [3H]-cocaine binding to Cocaine receptor in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24RPPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50455445(CHEMBL2112045)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Inhibition [3H]-cocaine binding to Cocaine receptor in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24RPPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50455445(CHEMBL2112045)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:Inhibition [3H]DA uptake in rat striatal synaptosomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24RPPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043312((1-Benzo[b]thiophen-2-yl-cyclohexyl)-cyclobutylmet...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043295((1-Benzo[b]thiophen-2-yl-cyclohexyl)-propyl-amine ...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043292((1-Benzo[b]thiophen-2-yl-cyclohexyl)-cyclopropylme...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50005534(1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043295((1-Benzo[b]thiophen-2-yl-cyclohexyl)-propyl-amine ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50455447(CHEMBL2112946)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:Inhibition [3H]DA uptake in rat striatal synaptosomes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24RPPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043312((1-Benzo[b]thiophen-2-yl-cyclohexyl)-cyclobutylmet...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043303((1-Benzo[b]thiophen-2-yl-cyclohexyl)-butyl-amine |...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043316(Allyl-(1-benzo[b]thiophen-2-yl-cyclohexyl)-amine |...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043317((1-Benzo[b]thiophen-2-yl-cyclohexyl)-(3-methyl-but...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50455444(CHEMBL2112945)copy SMILEScopy InChI
Affinity DataIC50: 9.90nMAssay Description:Inhibition [3H]-cocaine binding to Cocaine receptor in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24RPPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50455443(CHEMBL2112944)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition [3H]-cocaine binding to Cocaine receptor in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB24RPPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043316(Allyl-(1-benzo[b]thiophen-2-yl-cyclohexyl)-amine |...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50005534(1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50005534(1-(1-(benzo[b]thiophen-2-yl)cyclohexyl)piperidine ...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043309((1-Benzo[b]thiophen-2-yl-cyclohexyl)-diethyl-amine...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Tested for radioligand [3H]BTCP displacement from dopamine transporter in rat forebrainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043309((1-Benzo[b]thiophen-2-yl-cyclohexyl)-diethyl-amine...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040193(1-(1-Benzo[b]thiophen-2-yl-cyclohexyl)-pyrrolidine...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]cocaine binding to rat forebrain dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040191(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-pyrrolidin...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043317((1-Benzo[b]thiophen-2-yl-cyclohexyl)-(3-methyl-but...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50043317((1-Benzo[b]thiophen-2-yl-cyclohexyl)-(3-methyl-but...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Tested for inhibition of radioligand [3H]dopamine (DA) uptake in rat synaptosomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KK9CFJPubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50040199(1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-piperidine...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Displacement of [3H]BTCP (1-[1-(2-benxo[b]thienyl)cyclohexyl]piperidine) from rat forebrain dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23F4Q98PubMed
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