Compile Data Set for Download or QSAR
Found 52 with Last Name = 'harris' and Initial = 'me'
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153698(L-CS319)copy SMILEScopy InChI
Affinity DataKi:  3.70E+3nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153700(L-VC26)copy SMILEScopy InChI
Affinity DataKi:  3.80E+3nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513WZZPubMed
TargetVIM-24(Klebsiella pneumoniae (Enterobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153700(L-VC26)copy SMILEScopy InChI
Affinity DataKi:  4.90E+3nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513WZZPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247408(CHEMBL4067105)copy SMILEScopy InChI
Affinity DataKi:  5.00E+3nMAssay Description:Competitive inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153699(D-CS319)copy SMILEScopy InChI
Affinity DataKi:  5.40E+3nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513WZZPubMed
TargetVIM-24(Klebsiella pneumoniae (Enterobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153698(L-CS319)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
TargetVIM-24(Klebsiella pneumoniae (Enterobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153699(D-CS319)copy SMILEScopy InChI
Affinity DataKi:  1.10E+4nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513WZZPubMed
TargetVIM-24(Klebsiella pneumoniae (Enterobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153701(D-VC26)copy SMILEScopy InChI
Affinity DataKi:  1.20E+4nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513WZZPubMed
TargetMetallo-beta-lactamase VIM-2(Pseudomonas aeruginosa (g-Proteobacteria))
Louis Stokes Cleveland Veterans Affairs Medical Center

LigandPNGBDBM153701(D-VC26)copy SMILEScopy InChI
Affinity DataKi:  1.40E+4nMAssay Description:The Ki for each inhibitor was determined by direct competition assays under steady-state conditions. The initial velocity was measured in the presenc...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2513WZZPubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50198892(3-AP | 3-aminopyridine-2-carboxaldehyde thiosemica...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibition of human RRM2 expressed in Escherichia coli BL21-codon plus(DE3) using [14C]-ADP as substrate after 3 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247442(CHEMBL3193213)copy SMILEScopy InChI
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247435(CHEMBL4073197)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247434(CHEMBL1958235)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247436(CHEMBL4100050)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247408(CHEMBL4067105)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247441(CHEMBL4067759)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247433(CHEMBL4059739)copy SMILEScopy InChI
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247432(CHEMBL4077024)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247427(CHEMBL4064659)copy SMILEScopy InChI
Affinity DataIC50: 1.67E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247440(CHEMBL4091609)copy SMILEScopy InChI
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247426(CHEMBL4097201)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247424(CHEMBL4101599)copy SMILEScopy InChI
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500167(CHEMBL3747291)copy SMILEScopy InChI
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500166(CHEMBL3747319)copy SMILEScopy InChI
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247425(CHEMBL4070699)copy SMILEScopy InChI
Affinity DataIC50: 2.38E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500171(CHEMBL600902 | GNF-Pf-721)copy SMILEScopy InChI
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500170(CHEMBL3747217)copy SMILEScopy InChI
Affinity DataIC50: 2.72E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247408(CHEMBL4067105)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate by boronate affinity chromatographyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500168(CHEMBL3746072)copy SMILEScopy InChI
Affinity DataIC50: 3.22E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500174(CHEMBL3745866)copy SMILEScopy InChI
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247439(CHEMBL4075660)copy SMILEScopy InChI
Affinity DataIC50: 3.94E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247423(CHEMBL4064137)copy SMILEScopy InChI
Affinity DataIC50: 4.37E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500165(CHEMBL3746526)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500172(CHEMBL3746454)copy SMILEScopy InChI
Affinity DataIC50: 4.52E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500173(CHEMBL3746940)copy SMILEScopy InChI
Affinity DataIC50: 4.72E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500169(CHEMBL3746715)copy SMILEScopy InChI
Affinity DataIC50: 6.17E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247410(CHEMBL4077097)copy SMILEScopy InChI
Affinity DataIC50: 7.01E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247411(CHEMBL4087321)copy SMILEScopy InChI
Affinity DataIC50: 8.68E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247422(CHEMBL4085702)copy SMILEScopy InChI
Affinity DataIC50: 9.41E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247412(CHEMBL4074537)copy SMILEScopy InChI
Affinity DataIC50: 9.52E+4nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247437(CHEMBL4065911)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247421(CHEMBL4102759)copy SMILEScopy InChI
Affinity DataIC50: 1.22E+5nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase subunit M2(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247408(CHEMBL4067105)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of human RRM2 expressed in Escherichia coli BL21-codon plus(DE3) using [14C]-ADP as substrate after 3 mins by liquid scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247409(CHEMBL4093660)copy SMILEScopy InChI
Affinity DataIC50: 1.31E+5nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247438(CHEMBL4084809)copy SMILEScopy InChI
Affinity DataIC50: 2.98E+5nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247420(CHEMBL4095000)copy SMILEScopy InChI
Affinity DataIC50: 6.87E+5nMAssay Description:Inhibition of human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL using [14C]-ADP as substrate after 3 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50017811(CHEMBL467 | HU | US10155732, Compound HU | hydroxy...)copy SMILEScopy InChI
Affinity DataIC50: 9.97E+5nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMedDrugBank
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500165(CHEMBL3746526)copy SMILEScopy InChI
Affinity DataKd:  5.53E+4nMAssay Description:Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50247408(CHEMBL4067105)copy SMILEScopy InChI
Affinity DataKd:  3.70E+4nMAssay Description:Binding affinity to human RRM1 expressed in Escherichia coli BL21-codon plus(DE3)-RIL by fluorescence spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W098CBPubMed
TargetRibonucleoside-diphosphate reductase large subunit(Homo sapiens (Human))
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500171(CHEMBL600902 | GNF-Pf-721)copy SMILEScopy InChI
Affinity DataKd:  3.56E+4nMAssay Description:Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2M5MPubMed
Displayed 1 to 50 (of 52 total ) | Next | Last >>
Jump to: