Compile Data Set for Download or QSAR
Found 202 with Last Name = 'finley' and Initial = 'mf'
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataKi:  300nMAssay Description:Inhibition of human carbonic anhydrase 2 by ThermoFluor methodMore data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465794(CHEMBL4288564)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465788(CHEMBL4292697)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465792(CHEMBL4279774)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465796(CHEMBL4290426)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465791(CHEMBL4289288)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465800(CHEMBL4282095)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465798(CHEMBL4278633)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465789(CHEMBL4293756)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465786(CHEMBL4283590)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465802(CHEMBL4294178)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465793(CHEMBL4277584)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465795(CHEMBL4285527)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465801(CHEMBL4291986)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465797(CHEMBL4280661)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465798(CHEMBL4278633)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465790(CHEMBL4284117)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465792(CHEMBL4279774)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465799(CHEMBL4285877)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465803(CHEMBL4292404)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465792(CHEMBL4279774)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465793(CHEMBL4277584)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465800(CHEMBL4282095)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465787(CHEMBL4292985)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Cav2.2 (unknown origin) expressed in HEK293 cells assessed as decrease in KCl depolarization-induced Ca2+ influx measured for 5 mins by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465786(CHEMBL4283590)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465803(CHEMBL4292404)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465803(CHEMBL4292404)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465796(CHEMBL4290426)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465800(CHEMBL4282095)copy SMILEScopy InChI
Affinity DataIC50: 61nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465793(CHEMBL4277584)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465788(CHEMBL4292697)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465798(CHEMBL4278633)copy SMILEScopy InChI
Affinity DataIC50: 91nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465794(CHEMBL4288564)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465788(CHEMBL4292697)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465796(CHEMBL4290426)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465786(CHEMBL4283590)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465797(CHEMBL4280661)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465794(CHEMBL4288564)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465797(CHEMBL4280661)copy SMILEScopy InChI
Affinity DataIC50: 740nMAssay Description:Inhibition of low frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465790(CHEMBL4284117)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL
LigandPNGBDBM10887(Sulfamate 7 | Topiramate (TPM) | US11535599, Examp...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydration assayMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50203652(CHEMBL3909872)copy SMILEScopy InChI
Affinity DataIC50: 3.28E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WZ2PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL
LigandPNGBDBM50310430(CHEMBL1084919 | N-[(4-bromo-1-benzothien-3-yl)meth...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9BQDPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL
LigandPNGBDBM50310434(CHEMBL1077117 | N-(1-benzofuran-3-ylmethyl)sulfami...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 by CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9BQDPubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Johnson& Johnson Pharmaceutical Research& Development

Curated by ChEMBL
LigandPNGBDBM50310436(CHEMBL1084675 | N-[(5-chloro-1-benzothien-3-yl)met...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human carbonic anhydrase 2 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21J9BQDPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50203652(CHEMBL3909872)copy SMILEScopy InChI
Affinity DataIC50: 9.13E+3nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WZ2PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50203652(CHEMBL3909872)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WZ2PubMed
TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Homo sapiens (Human))
Janssen Research & Development, L.L.C.

Curated by ChEMBL
LigandPNGBDBM50465802(CHEMBL4294178)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of high frequency stimulation-induced Cav2.2 (unknown origin) expressed in HEK293 cells at -80 mV holding membrane potential by automated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571FP9PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50203653(CHEMBL3896657)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of Cav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WZ2PubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50203654(CHEMBL3968947)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of Nav1.5 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WZ2PubMed
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