Compile Data Set for Download or QSAR
Found 240 with Last Name = 'klein' and Initial = 'mg'
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166601(CHEMBL3798679)copy SMILEScopy InChI
Affinity DataIC50: 0.460nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166602(CHEMBL3800310)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367855(CHEMBL4175929)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of GST-tagged human CDK2/CCNA2 (04 to 103 residues) pre-incubated for 5 mins before addition of histone H1 substrate and [gamma-33P]ATP an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged GSK-3beta (unknown origin) expressed in baculovirus preincubated for 5 mins using GSK3 substrate peptide measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal GST-tagged human TrkA expressed in baculovirus preincubated for 5 mins measured after 10 mins in presence of ATP by AlphaScr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of CLK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCalpha (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCdelta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCbeta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetCyclin-dependent kinase 13/Cyclin-K(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367676(CHEMBL4160662)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK13 (1 to 1512 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367737(CHEMBL4173631)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of GST-tagged human CDK2/CCNA2 (04 to 103 residues) pre-incubated for 5 mins before addition of histone H1 substrate and [gamma-33P]ATP an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612293(CHEMBL5265996)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of PKCtheta in human Jurkat cells after overnight incubation by luminescence analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612290(CHEMBL5288132)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50163919(CHEMBL3798266)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
Takeda California, Inc.

Curated by ChEMBL
LigandPNGBDBM50266936(CHEMBL4078601)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of mouse ATX using TG-mTMP as substrate after 2 hrs by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319ZCTPubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367857(CHEMBL4159417)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of GST-tagged human CDK9/CycT1 (04 to 110 residues) assessed as reduction in ATP-dependent ULight-4E-BP1 (Thr37/Thr46) substrate peptide p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetCyclin-C(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged human CDK8/CycC (04 to 109 residues) using kinase tracer 236 probe incubated for 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166601(CHEMBL3798679)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of PKCtheta in human Jurkat cells after overnight incubation by luminescence analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mus musculus)
Takeda California, Inc.

Curated by ChEMBL
LigandPNGBDBM50266937(CHEMBL4095125)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of mouse ATX using TG-mTMP as substrate after 2 hrs by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319ZCTPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367857(CHEMBL4159417)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibition of GST-tagged human CDK2/CCNA2 (04 to 103 residues) pre-incubated for 5 mins before addition of histone H1 substrate and [gamma-33P]ATP an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612292(CHEMBL5268272)copy SMILES
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612295(CHEMBL5267547)copy SMILES
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50612291(CHEMBL5278471)copy SMILES
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367955(CHEMBL4174716)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of GST-tagged human CDK2/CCNA2 (04 to 103 residues) pre-incubated for 5 mins before addition of histone H1 substrate and [gamma-33P]ATP an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367873(CHEMBL4169139)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of GST-tagged human CDK2/CCNA2 (04 to 103 residues) pre-incubated for 5 mins before addition of histone H1 substrate and [gamma-33P]ATP an...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367957(CHEMBL4174715)copy SMILEScopy InChI
Affinity DataIC50: 44nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50164188(CHEMBL3799399)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetCyclin-K/Cyclin-dependent kinase 12(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367676(CHEMBL4160662)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetCyclin-dependent kinase 13/Cyclin-K(Homo sapiens (Human))
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 57nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK13 (1 to 1512 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367685(CHEMBL4172363)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50164176(CHEMBL3798713)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514710(CHEMBL4555677)copy SMILEScopy InChI
Affinity DataIC50: 62nMMore data for this Ligand-Target Pair
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514710(CHEMBL4555677)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 12(Homo sapiens)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367845(CHEMBL4173254)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367707(CHEMBL4167916)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetU5 small nuclear ribonucleoprotein 200 kDa helicase(Homo sapiens (Human))
Takeda California Inc.

Curated by ChEMBL
LigandPNGBDBM50239869(CHEMBL4084949)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged BRR2 RNA dependent ATPase activity expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC925GPubMed
TargetDeoxyhypusine synthase(Homo sapiens)TBA
LigandPNGBDBM50514715(CHEMBL4543218)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of human N-terminal His6-tagged TEV protease site linked DHPS expressed in Escherichia coli BL21 (DE3) assessed as reduction in radiolabel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35Z1VPubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
Takeda Pharmaceutical Company Limited

Curated by ChEMBL
LigandPNGBDBM50367684(CHEMBL4162567)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of N-terminal FLAG-tagged human full-length CDK12 (1 to 1490 residues)/N-terminal His-tagged CycK (1 to 580 residues) expressed in Sf9 cel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX1G6FPubMed
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal FLAG-tagged FAK cytoplasmic domain (unknown origin) expressed in baculovirus preincubated for 5 mins measured after 20 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166599(CHEMBL3800082)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal FLAG-tagged PKCtheta (unknown origin) expressed in baculovirus preincubated for 5 mins using fluorescein-PKC substrate measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human c-Met preincubated for 5 mins measured after 10 mins in presence of ATP by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Takeda Pharmaceutical Company, Ltd

Curated by ChEMBL
LigandPNGBDBM50166588(CHEMBL3798011)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of full length N-terminal His-tagged recombinant human SRC preincubated for 5 mins measured after 10 mins in presence of ATP by AlphaScree...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27W6F29PubMed
Displayed 1 to 50 (of 240 total ) | Next | Last >>
Jump to: