Compile Data Set for Download or QSAR
Found 214 with Last Name = 'ismaili' and Initial = 'mh'
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312809(1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50457820(CHEMBL4216289)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50457816(CHEMBL4215425)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312763(1-[4-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086681(CHEMBL3426309)copy SMILES
Affinity DataKi:  0.0900nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50015266(CHEMBL3263053)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312785(1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  0.130nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312765(5-fluoro-1-[4-[2-[(3R)-3-hy- droxy-1-methyl-2-oxo-...)copy SMILEScopy InChI
Affinity DataKi:  0.170nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037076(CHEMBL3355737)copy SMILES
Affinity DataKi:  0.170nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312788(1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  0.180nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086604(CHEMBL3426308)copy SMILES
Affinity DataKi:  0.200nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022940(CHEMBL3298373)copy SMILEScopy InChI
Affinity DataKi:  0.200nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50457815(CHEMBL4211840)copy SMILEScopy InChI
Affinity DataKi:  0.230nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312711(1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  0.230nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312764(1-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  0.230nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037066(CHEMBL3355728)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312723(5-fluoro-1-[3-[2-[(3R)-3-hy- droxy-1-methyl-2-oxo-...)copy SMILEScopy InChI
Affinity DataKi:  0.270nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086671(CHEMBL3426305)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086671(CHEMBL3426305)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086659(CHEMBL3426303)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086659(CHEMBL3426303)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086605(CHEMBL3426307)copy SMILES
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086676(CHEMBL3426304)copy SMILEScopy InChI
Affinity DataKi:  0.300nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037077(CHEMBL3355738)copy SMILES
Affinity DataKi:  0.380nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50457818(CHEMBL4211560)copy SMILEScopy InChI
Affinity DataKi:  0.420nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086680(CHEMBL3426306)copy SMILEScopy InChI
Affinity DataKi:  0.5nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50457817(CHEMBL4214032)copy SMILEScopy InChI
Affinity DataKi:  0.590nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022932(CHEMBL3298371)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022934(CHEMBL3298375)copy SMILEScopy InChI
Affinity DataKi:  0.700nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022927(CHEMBL3298370)copy SMILEScopy InChI
Affinity DataKi:  0.800nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312762(1-[4-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  0.860nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086669(CHEMBL3426301)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086669(CHEMBL3426301)copy SMILEScopy InChI
Affinity DataKi:  0.900nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50015271(CHEMBL3263036)copy SMILEScopy InChI
Affinity DataKi:  1.10nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037070(CHEMBL3355732)copy SMILES
Affinity DataKi:  1.20nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022929(CHEMBL3298376)copy SMILEScopy InChI
Affinity DataKi:  1.20nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50457812(CHEMBL4217923)copy SMILEScopy InChI
Affinity DataKi:  1.30nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037074(CHEMBL3355736)copy SMILES
Affinity DataKi:  1.60nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037071(CHEMBL3355733)copy SMILES
Affinity DataKi:  1.80nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50457811(CHEMBL4210461)copy SMILEScopy InChI
Affinity DataKi:  2nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037068(CHEMBL3355730)copy SMILES
Affinity DataKi:  2.30nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086667(CHEMBL3426302)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50086667(CHEMBL3426302)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022931(CHEMBL3298369)copy SMILEScopy InChI
Affinity DataKi:  3nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037063(CHEMBL3355726)copy SMILES
Affinity DataKi:  4nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50442147(CHEMBL2441269)copy SMILEScopy InChI
Affinity DataKi:  4nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM312799(3-[3-[2-[(3R)-3-hydroxy-1- methyl-2-oxo-pyrrolidin...)copy SMILEScopy InChI
Affinity DataKi:  4.70nMAssay Description:Inhibition of NIK (unknown origin) expressed in baculovirus infected insect cells assessed as reduction in hydrolysis of ATP to ADP after 1 to 2 hrs ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PV6P00PubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50037069(CHEMBL3355731)copy SMILES
Affinity DataKi:  5.30nMAssay Description:Inhibition of GST-tagged full-length ITK (unknown origin) using Ac-EFPIYDFLPAKKK-NH2 as substrate after 35 mins by LC/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GNTPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022933(CHEMBL3298288)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Inhibition of GST-tagged recombinant full length human ITK using AcEFPIYDFLPAKKK-NH2 as substrate after 35 mins by Morrison plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7BTHPubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Genentech Inc.

Curated by ChEMBL
LigandPNGBDBM50022933(CHEMBL3298288)copy SMILEScopy InChI
Affinity DataKi:  5.30nMAssay Description:Inhibition of GST-tagged full length ITK (unknown origin) using BLK peptide as substrate after 35 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5J7TPubMed
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