Compile Data Set for Download or QSAR
Found 200 with Last Name = 'heron' and Initial = 'mi'
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324200(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324215((+/-)-(3SR,3aRS)-2-(4-Cyano-3-methylphenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324201(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324216((+/-)-(3SR,3aRS)-2-(4-Cyano-3-methoxyphenyl)-3-cyc...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324117(CHEMBL1215552 | Methyl 2-((1H-Imidazol-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50228080(2',15'-dimethyl-5,5'-dioxo-(9'R)-spiro[tetrahydrof...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324202(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324199(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324212((+/-)-(3RS,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324196(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324157(CHEMBL1215549 | Methyl 4-(2-Chloro-4-fluorophenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324211((+/-)-(3RS,3aSR)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324210((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324224((3S,3aR)-2-(3-Chloro-4-cyanophenyl)-3-cyclopentyl-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324198(2-Chloro-4-[(5R)-1-(3-chloro-4-cyanophenyl)-5-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324226((3S,3aR)-2-(4-Cyano-3-methylphenyl)-3-cyclopentyl-...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324163(4-[(5R)-5-(4-Fluorophenyl)-3-(2-oxo-2,3-dihydro-1,...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Displacement of [3H]dofetilide from human ERG at 10 uMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324227(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophen...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324165(4-[(5R)-3-(2,4-Dimethyl-1,3-thiazol-5-yl)-5-(4-flu...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324223((+/-)-(3RS,3aSR)-2-(4-Cyano-3-methylphenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324163(4-[(5R)-5-(4-Fluorophenyl)-3-(2-oxo-2,3-dihydro-1,...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324209((3R,3aR)-2-(3-Chloro-4-cyanophenyl)-3-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324116((R)-Methyl 2-((1H-Tetrazol-1-yl)methyl)-4-(2-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324158(CHEMBL1215550 | Methyl 4-(2-Chloro-4-fluorophenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324197(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 52nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324195((+/-)-4-[1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324118(CHEMBL1215620 | Methyl 2-((1H-Pyrazol-1-yl)methyl)...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324180((+/-)-4-[1-(4-Cyano-3-methylphenyl)-5-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324178((+/-)-4-[1-(3-Chloro-4-cyanophenyl)-5-(4-fluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324162((+/-)-4-[5-(4-Fluorophenyl)-3-(2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324151(CHEMBL1215480 | Methyl 2-Butyl-4-(2-chlorophenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50318295(CHEMBL1097751 | tert-Butyl (4R)-4-(2-Chloro-4-fluo...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324149(CHEMBL1215406 | Methyl 4-(2-Chlorophenyl)-5-cyano-...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324115(CHEMBL1215622 | Methyl 2-((1H-Tetrazol-1-yl)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324221((+/-)-(3RS,3aSR)-2-(3-Chloro-4-cyanophenyl)-3-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324205(4-[(4S,5S)-1-(3-Chloro-4-cyanophenyl)-5-cyclopenty...)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324139(3-tert-butyl 5-methyl 4-(2-chloro-4-fluorophenyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 78nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324203(4-[(5R)-1-(3-Chloro-4-cyanophenyl)-5-cyclopentyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324166((+/-)-4-[1-(4-Cyanophenyl)-5-(4-fluorophenyl)-4,5-...)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324160((+/-)-(3SR,3aRS)-2-(4-Cyanophenyl)-3-cyclopentyl-3...)copy SMILEScopy InChI
Affinity DataIC50: 89nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324146(CHEMBL1215403 | Methyl 4-(2-Chloro-4-fluorophenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324119(CHEMBL1215621 | Methyl 2-((1H-1,2,4-Triazol-1-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324157(CHEMBL1215549 | Methyl 4-(2-Chloro-4-fluorophenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Antagonist activity at androgen receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324170(4-[(5R)-1-(4-Cyanophenyl)-5-(4-fluorophenyl)-4,5-d...)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50318300(CHEMBL1095097 | EPLERENONE | SC-66110)copy SMILEScopy InChI
Affinity DataIC50: 122nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324119(CHEMBL1215621 | Methyl 2-((1H-1,2,4-Triazol-1-yl)m...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50318298((+)-(R)-3-tert-butyl 5-methyl 2,6-dimethyl-4-(3-ni...)copy SMILEScopy InChI
Affinity DataIC50: 126nMAssay Description:Antagonist activity at mineralocorticoid receptor LBD expressed in human HUH7 cells coexpressing GAL4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XW4KSTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50324214((+/-)-(3SR,3aRS)-2-(3-Chloro-4-cyanophenyl)-3-(tet...)copy SMILEScopy InChI
Affinity DataIC50: 127nMAssay Description:Antagonist activity at Gal4-tagged mineralocorticoid receptor expressed in human Huh7 cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43V2TPubMed
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