Compile Data Set for Download or QSAR
Found 265 with Last Name = 'ashton' and Initial = 'mj'
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM14775(3-(cyclopentyloxy)-N-(3,5-dichloropyridin-4-yl)-4-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041849(3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(3,5-dichloro-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041849(3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(3,5-dichloro-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054959((4aS,4bR,5S,6aS,6bR,9aR)-4b-Fluoro-5-hydroxy-4a,6a...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054966((4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-4a...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50407988(CHEMBL2112857)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041853(3-Cyclopentyloxy-N-(3,5-dichloro-1-oxy-pyridin-4-y...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054953((4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-4a...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054961((4aS,4bR,5S,6aS,6bR,9aR,12S)-4b,12-Difluoro-5-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054964((4aS,4bR,5S,6aS,6bR,8R,9aR,12S)-4b,12-Difluoro-6b-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054955((4aS,4bR,5S,6aS,6bR,8R,9aR,12S)-4b,12-Difluoro-5-h...)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50369181(TIPREDANE)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054960((4aS,4bR,5S,6aS,6bR,8R,9aR,12S)-4b,12-Difluoro-5-h...)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50354850(BUDESONIDE | US10869929, Compound Budesonide | US1...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054952((4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-6b...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054962((4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-6b-fluoromet...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054963((4aS,4bR,5S,6aS,6bR,8R,9aR)-6b-Ethylsulfanyl-4b-fl...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051895(2-(2,4-Dioxa-spiro[5.5]undec-3-yl)-4,5-diphenyl-1H...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB160CPubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50407989(CHEMBL2112850)copy SMILEScopy InChI
Affinity DataIC50: 4.30nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50354849(CCI-18781 | Cutivate | FLUTICASONE PROPIONATE | Fl...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50407990(CHEMBL2112858)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054967((4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-6b...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041831(3-Cyclopentyloxy-N-(3,5-dibromo-pyridin-4-yl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041846(3-Butoxy-N-(3,5-dichloro-pyridin-4-yl)-4-methoxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50033969(3-(2,4-Difluoro-phenyl)-1-[5-(4,5-diphenyl-1H-imid...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from HepG2 microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051894(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% of the Acyl coenzyme A:cholesterol acyltransferase 1 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB160CPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041886(3-(Bicyclo[2.2.1]hept-2-yloxy)-N-(2,6-dichloro-phe...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50280419(2-[3-(1-Methyl-1H-imidazole-2-sulfonyl)-propylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054957((4aS,4bR,5S,6aS,6bR,8R,9aR)-4b-Fluoro-5-hydroxy-4a...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
TargetSterol O-acyltransferase 1(Cricetulus griseus)
TBA

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from hamster liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50280416(2-[3-(1-Methyl-1H-imidazol-2-ylsulfanyl)-propylsul...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051897(2-(5,5-Diethyl-[1,3]dioxan-2-yl)-4,5-diphenyl-1H-i...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB160CPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041847(CHEMBL295976 | N-(3-Chloro-pyridin-4-yl)-3-cyclope...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051881(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit liver Acyl coenzyme A:choleste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB160CPubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041875(3-Cyclopentyloxy-N-(3,5-dichloro-2,6-difluoro-pyri...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetGlucocorticoid receptor(RAT)
Rh£ne-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50054951((4aS,4bR,5S,6aS,6bR,9aR)-4b-Fluoro-5-hydroxy-4a,6a...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Steroid binding against the rat thymus glucocorticoid receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23779C8PubMed
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041838(3-(cyclopentyloxy)-N-(2,6-dichlorophenyl)-4-methox...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50280422(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29WXG
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051881(1-{4-[2-(4,5-Diphenyl-1H-imidazol-2-yl)-5-methyl-[...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit artery Acyl coenzyme A:cholest...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB160CPubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase 1 from rat liver.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB160CPubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50003845(6-(4,5-Diphenyl-1H-imidazol-2-ylsulfanylmethyl)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of acyl coenzyme A:cholesterol acyltransferase (ACAT) activity in rat liver microsomeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q218374HPubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Concentration required for the inhibition of Cholesterol O-acyl transferase from cholesterol fed rabbit gutMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
Target3',5'-cyclic-AMP phosphodiesterase(Sus scrofa)
Rhône-Poulenc Rorer Central Research

Curated by ChEMBL
LigandPNGBDBM50041869(3-Cyclopentyloxy-N-(3,5-dimethyl-pyridin-4-yl)-4-m...)copy SMILEScopy InChI
Affinity DataIC50: 35nMAssay Description:Inhibitory potency against pig aortic PDE IVMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9P5FPubMed
TargetSterol O-acyltransferase 1(Rattus norvegicus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50280418(2-[4-(1-Methyl-1H-imidazol-2-ylsulfanyl)-butylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Compound was evaluated for inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase in microsomes from rabbit artery.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29WXG
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Concentration required for the inhibition of cholesterol O-acyl transferase (ACAT) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP535G
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit artery Acyl coenzyme A:cholest...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB160CPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Rhône-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50051901(1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibitory concentration of the compound was evaluated as concentration required to inhibit 50% activity of the rabbit liver Acyl coenzyme A:choleste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TB160CPubMed
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