Found 64 with Last Name = 'witty' and Initial = 'mj' 
Affinity DataIC50: 400nMAssay Description:Inhibition of CYP2D6-mediated dextromethorphan O-demethylation in human liver microsomes by LCMS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP1A2-mediated phencetin o-de-ethylation in human liver microsomes by LCMS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human ERG channel expressed in Chinese hamster lung cells after 6 to 7 mins by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human ERG expressed in Chinese hamster CHL cells by perforated patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiologyMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiologyMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by IonWorks assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ERG potassium channel by ionworks patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 6.80E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human ERG by patch clamp electrophysiologyMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Binding affinity to full length human ERG expressed in CHO cells after 6 to 7 mins by IonWorks assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9-mediated Tolbutamide methlyhydroxylation in human liver microsomes by LCMS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG by IonWorks patch clamp electrophysiology methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ERG channel by patch clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2C19-mediated (S)-mephenytoin 4'-hydroxylation in human liver microsomes by LCMS analysisMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University of Cape Town
Curated by ChEMBL
University of Cape Town
Curated by ChEMBL
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of human ERG expressed in chinese hamster lung cells by IonWorks patch clamp electrophysiology assayMore data for this Ligand-Target Pair
