Compile Data Set for Download or QSAR
Found 24 with Last Name = 'bennett' and Initial = 'mk'
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50005795(2,8-Diamino-9-thiophen-2-ylmethyl-1,9-dihydro-puri...)copy SMILEScopy InChI
Affinity DataKi:  67nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50368609(CHEMBL604660)copy SMILEScopy InChI
Affinity DataKi:  176nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50368611(CHEMBL604864)copy SMILEScopy InChI
Affinity DataKi:  200nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50005916(2,6-diamino-7-(thien-3-ylmethyl)-3,5-dihydro-4H-py...)copy SMILEScopy InChI
Affinity DataKi:  830nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50230691(CHEMBL3143996)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50230690(CHEMBL3143997)copy SMILEScopy InChI
Affinity DataKi:  2.90E+3nMAssay Description:Ability to inhibit purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277781((2S)-2-[(2S)-2-[(5-ethoxy-1,2-oxazol-3-yl)formamid...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50069989((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277889(CARFILZOMIB | CHEMBL451887)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMedDrugBank
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277779(CHEMBL484003 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277815(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277816(3-methoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)...)copy SMILEScopy InChI
Affinity DataIC50: 36nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277780(5-ethoxy-N-((S)-3-methoxy-1-((S)-3-methoxy-1-((S)-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277818(2-Me-5-thiazole-Ser(OMe)-Ser(OMe)-Phe-ketoepoxide ...)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277778(CHEMBL484002 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 93nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277733((2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(5-methyl-1,2-...)copy SMILEScopy InChI
Affinity DataIC50: 238nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277734(CHEMBL484157 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 607nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Proteolix, Inc.

Curated by ChEMBL
LigandPNGBDBM50277817(CHEMBL483740 | N-((S)-3-methoxy-1-((S)-3-methoxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 784nMAssay Description:Inhibition of chymotrypsin-like activity of LMP7 immunoproteasome by proteasome active site ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1KS0PubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50005916(2,6-diamino-7-(thien-3-ylmethyl)-3,5-dihydro-4H-py...)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50005924(2,6-Diamino-7-thiophen-2-ylmethyl-3,5-dihydro-pyrr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50404028(CHEMBL2021376)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50005919(2,6-Diamino-7-benzyl-3,5-dihydro-pyrrolo[3,2-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50005918(2,6-Diamino-7-furan-2-ylmethyl-3,5-dihydro-pyrrolo...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed
TargetPurine nucleoside phosphorylase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50005921(2,6-Diamino-7-(2-methoxy-benzyl)-3,5-dihydro-pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 3.14E+4nMAssay Description:Compound was tested for the inhibitory activity against purine nucleoside phosphorylase (PNP)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5GPHPubMed