Compile Data Set for Download or QSAR
Found 29 with Last Name = 'clements' and Initial = 'mk'
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM81801(CAS_5283121 | LTC4 | NSC_5283121)copy SMILEScopy InChI
Affinity DataKi:  3.35nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP01BHPubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM50292408((R-(R*,S*-(E,E,Z,Z)))-N-(S-(1-(4-Carboxy-1-hydroxy...)copy SMILEScopy InChI
Affinity DataKi:  3.48nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP01BHPubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM50297387((5S,6R,7E,9E,11Z,14Z)-6-(cystein-S-yl)-5-hydroxyic...)copy SMILEScopy InChI
Affinity DataKi:  693nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP01BHPubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM85674(CAS_103177-37-3 | NSC_115100 | Pranlukast)copy SMILEScopy InChI
Affinity DataKi:  3.62E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP01BHPubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP01BHPubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM50013889((5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP01BHPubMed
TargetLeukotriene B4 receptor 2(Homo sapiens (Human))
University of Virginia

Curated by PDSP Ki Database
LigandPNGBDBM85673(CAS_5311297 | Montelukast | NSC_5311297)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP01BHPubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells measured after 5 to 10 mins post compound washout by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242510(CHEMBL4095146)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of 50% inactivated mouse Nav1.7alpha incubated for 5 mins measured at 10 secs interval by PatchXpress automated electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 2 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of Nav1.2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]PIA binding to rat cortical adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Inhibition of NaV1.7 channel in human DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242510(CHEMBL4095146)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242508(CHEMBL4084948)copy SMILEScopy InChI
Affinity DataIC50: 74nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Mus musculus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)copy SMILEScopy InChI
Affinity DataIC50: 82nMAssay Description:Inhibition of NaV1.7 channel in mouse DRG neurons assessed as reduction of TTX-sensitive current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242504(CHEMBL4090017)copy SMILEScopy InChI
Affinity DataIC50: 134nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242506(CHEMBL4077789)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242507(CHEMBL4102898)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242502(CHEMBL4082170)copy SMILEScopy InChI
Affinity DataIC50: 486nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242505(CHEMBL4102052)copy SMILEScopy InChI
Affinity DataIC50: 535nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242501(CHEMBL4060266)copy SMILEScopy InChI
Affinity DataIC50: 815nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242511(CHEMBL4071639)copy SMILEScopy InChI
Affinity DataIC50: 970nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Rattus norvegicus)
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242509(CHEMBL4068937)copy SMILEScopy InChI
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of NaV1.7 channel in rat DRG neurons assessed as reduction of TTX-sensitive sodium current by whole cell patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242503(CHEMBL4098657)copy SMILEScopy InChI
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50240267(CHEMBL2325014)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.7alpha expressed in HEK293 cells measured after 5 to 10 mins post compound washout by PatchXpress automated ...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242511(CHEMBL4071639)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242502(CHEMBL4082170)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50242501(CHEMBL4060266)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 50% inactivated human Nav1.5alpha expressed in HEK293 cells incubated for 5 mins measured at 10 secs interval by PatchXpress automated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SN0CD7PubMed