Compile Data Set for Download or QSAR
Found 97 with Last Name = 'shaw' and Initial = 'mk'
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006409(CHEMBL2367478 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006407(CHEMBL2367472 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006407(CHEMBL2367472 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042104(1-(2,6-Diisopropyl-phenyl)-3-(1-thiophen-2-yl-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042121(1-(2-Isopropyl-6-methyl-phenyl)-3-(1-phenyl-cyclop...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50038526(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopentyl...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042119(1-(2,6-Diisopropyl-phenyl)-3-(2-ethyl-2-phenyl-but...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006411(CHEMBL2367470 | Sodium; 7-[5-(4-fluoro-phenyl)-1-p...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042137(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042098(1-(2,6-Diisopropyl-phenyl)-3-(1-thiophen-3-yl-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042085(1-(2-tert-Butyl-6-methyl-phenyl)-3-(1-phenyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042103(1-(2-Ethyl-6-isopropyl-phenyl)-3-(1-phenyl-cyclohe...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM34168(LOVASTATIN | MLS000069585 | SMR000058779 | US91151...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006408(CHEMBL303515 | Lovastatin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042132(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclohexylm...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042080(1-(2,6-Diisopropyl-phenyl)-3-(2,2-diphenyl-ethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006410(CHEMBL2367477 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006410(CHEMBL2367477 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50011041(6-{2-[6-Chloro-4-(4-fluoro-phenyl)-2-isopropyl-qui...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Compound was evaluated for the inhibition of HMG-CoA reductase (COR) in rats.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RHGPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042117(1-(2-Ethyl-6-isopropyl-phenyl)-3-(1-phenyl-cyclope...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50011036((S)-((1S,7S,8S,8aR)-8-(2-((2R,4R)-4-hydroxy-6-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Compound was evaluated for the inhibition of HMG-CoA reductase (COR) in rats.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RHGPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042091(1-(2,6-Diisopropyl-phenyl)-3-(2-pentyl-2-phenyl-he...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042092(1-(2,6-Diisopropyl-phenyl)-3-(2-methyl-2-phenyl-pr...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042113(1-(2,6-Diisopropyl-phenyl)-3-(9H-fluoren-9-ylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042089(1-(2,6-Diisopropyl-phenyl)-3-(1-phenyl-cyclobutylm...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50004774((S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Compound was evaluated for the inhibition of HMG-CoA reductase (COR) in rats.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RHGPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM20688((3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042112(1-(2,6-Diisopropyl-phenyl)-3-(2-phenyl-2-propyl-pe...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042133(1-(2-Butyl-2-phenyl-hexyl)-3-(2,6-diisopropyl-phen...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50368146(CS-514 | Eptastatin Sodium | PRAVASTATIN SODIUM | ...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042078(1-(2,6-Diisopropyl-phenyl)-3-(1,2-diphenyl-ethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50011037(6-{2-[4-(4-Fluoro-phenyl)-2-isopropyl-quinolin-3-y...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Compound was evaluated for the inhibition of HMG-CoA reductase (COR) in rats.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RHGPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042128(1-(2,6-Diisopropyl-phenyl)-3-(1-naphthalen-1-yl-cy...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042139(1-(2,6-Diisopropyl-phenyl)-3-(2-naphthalen-2-yl-et...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006414(CHEMBL64962 | Sodium; 7-[5-(4-fluoro-phenyl)-3-iso...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042116(1-(2,6-Diisopropyl-phenyl)-3-(1,2,3,4-tetrahydro-n...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042115(1-(2,6-Diisopropyl-phenyl)-3-(2-naphthalen-1-yl-et...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042105(1-Benzhydryl-3-(2,6-diisopropyl-phenyl)-urea | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 45nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042084((1-Phenyl-cyclopentylmethyl)-carbamic acid 2,6-dii...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042083(1-(2,6-Diethyl-phenyl)-3-(1-phenyl-cyclohexylmethy...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50011039(6-{2-[4-(4-Fluoro-phenyl)-2-isopropyl-6-methoxy-qu...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:Compound was evaluated for the inhibition of HMG-CoA reductase (COR) in rats.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RHGPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042068(1-(2-tert-Butyl-6-methyl-phenyl)-3-(1-phenyl-cyclo...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042076(1-(2,6-Diethyl-phenyl)-3-(1-phenyl-cyclopentylmeth...)copy SMILEScopy InChI
Affinity DataIC50: 56nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042082(1-(2-Isopropyl-6-methyl-phenyl)-3-(1-phenyl-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006417(CHEMBL2367471 | Sodium; 7-[1-benzothiazol-2-yl-5-(...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50006415(CHEMBL2367475 | Sodium; 7-[5-(4-fluoro-phenyl)-3-i...)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Tested in vitro for the inhibition of HMG-CoA reductase from partially purified microsomal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HH6KN8PubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042124(1-(1-Benzyl-cyclopentyl)-3-(2,6-diisopropyl-phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042107(1-(2,6-Diisopropyl-phenyl)-3-(1,1-dimethyl-2-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 77nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50011038(6-{2-[6-Fluoro-4-(4-fluoro-phenyl)-2-isopropyl-1-o...)copy SMILEScopy InChI
Affinity DataIC50: 79nMAssay Description:Compound was evaluated for the inhibition of HMG-CoA reductase (COR) in rats.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J38RHGPubMed
TargetAcyl-CoA:cholesterol acyltransferase(Oryctolagus cuniculus)
Warner-Lambert Company

Curated by ChEMBL
LigandPNGBDBM50042088(1-(2,6-Diisopropyl-phenyl)-3-phenethyl-urea | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 88nMAssay Description:In vitro inhibition of Acyl coenzyme A:cholesterol acyltransferase using intestinal microsomes isolated from cholesterol fed rabbitsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M044GNPubMed
Displayed 1 to 50 (of 97 total ) | Next | Last >>
Jump to: